Eupergit® C, a carrier for immobilization of enzymes of industrial potential
Eupergit® C, a carrier for immobilization of enzymes of industrial potential
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DOI：
10.1016/s1381-1177(00)00124-7
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发表时间：
2000-09-04
影响因子：
--
通讯作者：
Kraemer, DM
中科院分区：
文献类型：
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作者：
Katchalski-Katzir, E;Kraemer, DM
Eupergit（R）C是一种由大孔珠组成的载体，用于固定具有工业潜力的酶，用于精细化学品和药物的生产。本文综述了Eupergit（R）C上固定化的各种酶与其他载体材料在工业生产实际底物浓度下各自生物催化剂的操作稳定性。在该领域的其他方面的相关性，如纯度的酶的需求被固定或类型的反应器最佳的给定的应用程序，也进行了讨论。本文介绍了一种在实验室规模上模拟工业搅拌釜式反应器（STR）性能的自动反应器，并说明了它在评价固定化酶性能方面的应用。(C)2000 Elsevier Science B.V.保留所有权利。
Eupergit(R) C is a carrier consisting of macroporous beads for immobilizing enzymes of industrial potential for the production of fine chemicals and pharmaceuticals. Various enzymes immobilized on Eupergit(R) C are reviewed in comparison with other carrier materials in terms of the operational stability of the respective biocatalysts at substrate concentrations realistic for industrial production. Other aspects of relevance in that field, such as the demand for purity of enzyme to be immobilized or type of reactor optimal for a given application, are also discussed. An automatic reactor simulating, at laboratory scale, the performance of an industrial stirred tank reactor (STR) is described, and its utilization for evaluating the performance of immobilized enzymes is shown. (C) 2000 Elsevier Science B.V. All rights reserved.