Neural correlates and neural computations in posterior parietal cortex during perceptual decision-making.
Neural correlates and neural computations in posterior parietal cortex during perceptual decision-making.
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DOI：
10.3389/fnint.2012.00086
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发表时间：
2012
影响因子：
3.5
通讯作者：
Meister ML
中科院分区：
文献类型：
--
作者：
Huk AC;Meister ML
最近的一系列工作已经发现，在相关的知觉决策和在猕猴外侧顶内区（LIP）的尖峰活动显着的成功。在这篇评论中，我们专注于LIP的神经计算的问题，没有回答的心理过程的神经相关的演示。我们强调了我们目前对精确神经计算的理解中的三个局限性：（1）现有数据尚未回答的经验问题;（2）与神经回路如何实际实现细胞外神经生理学和心理物理学所提出的机制有关的实现问题;以及（3）与使用控制良好的实验室任务相关的生态限制，以及它们是否为感觉运动计算提供了准确的窗口。这些问题促使采用一个更一般的“编码-解码框架”，这将是富有成效的更详细的沉思如何在LIP神经计算与知觉决策的形成。
A recent line of work has found remarkable success in relating perceptual decision-making and the spiking activity in the macaque lateral intraparietal area (LIP). In this review, we focus on questions about the neural computations in LIP that are not answered by demonstrations of neural correlates of psychological processes. We highlight three areas of limitations in our current understanding of the precise neural computations that might underlie neural correlates of decisions: (1) empirical questions not yet answered by existing data; (2) implementation issues related to how neural circuits could actually implement the mechanisms suggested by both extracellular neurophysiology and psychophysics; and (3) ecological constraints related to the use of well-controlled laboratory tasks and whether they provide an accurate window on sensorimotor computation. These issues motivate the adoption of a more general “encoding-decoding framework” that will be fruitful for more detailed contemplation of how neural computations in LIP relate to the formation of perceptual decisions.