Proceedings of the First Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness.
Proceedings of the First Curing Coma Campaign NIH Symposium: Challenging the Future of Research for Coma and Disorders of Consciousness.
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DOI：
10.1007/s12028-021-01260-x
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发表时间：
2021-07
影响因子：
3.5
通讯作者：
Curing Coma Campaign
中科院分区：
文献类型：
--
作者：
Claassen J;Akbari Y;Alexander S;Bader MK;Bell K;Bleck TP;Boly M;Brown J;Chou SH;Diringer MN;Edlow BL;Foreman B;Giacino JT;Gosseries O;Green T;Greer DM;Hanley DF;Hartings JA;Helbok R;Hemphill JC;Hinson HE;Hirsch K;Human T;James ML;Ko N;Kondziella D;Livesay S;Madden LK;Mainali S;Mayer SA;McCredie V;McNett MM;Meyfroidt G;Monti MM;Muehlschlegel S;Murthy S;Nyquist P;Olson DM;Provencio JJ;Rosenthal E;Sampaio Silva G;Sarasso S;Schiff ND;Sharshar T;Shutter L;Stevens RD;Vespa P;Videtta W;Wagner A;Ziai W;Whyte J;Zink E;Suarez JI;Curing Coma Campaign
昏迷和意识障碍（DoC）非常普遍，对全世界的患者、家庭和社会构成负担。作为治愈昏迷运动的一部分，神经重症监护协会与美国国立卫生研究院合作组织了一次研讨会，汇集了来自世界各地的专家，为DoC制定研究目标。会议沿着六个领域展开：（1）定义内型/表型，（2）生物标志物，（3）概念验证临床试验，（4）神经元定位，（5）长期恢复，（6）大型数据集。本论文集根据会议上的演示和讨论提出了可操作的研究目标。我们总结了背景，主要的研究差距，总体目标，小组讨论的方法，局限性和挑战，以及确定的交付成果。在线版本包含补充材料，可通过10.1007/s12028-021-01260-x获得。
Coma and disorders of consciousness (DoC) are highly prevalent and constitute a burden for patients, families, and society worldwide. As part of the Curing Coma Campaign, the Neurocritical Care Society partnered with the National Institutes of Health to organize a symposium bringing together experts from all over the world to develop research targets for DoC. The conference was structured along six domains: (1) defining endotype/phenotypes, (2) biomarkers, (3) proof-of-concept clinical trials, (4) neuroprognostication, (5) long-term recovery, and (6) large datasets. This proceedings paper presents actionable research targets based on the presentations and discussions that occurred at the conference. We summarize the background, main research gaps, overall goals, the panel discussion of the approach, limitations and challenges, and deliverables that were identified. The online version contains supplementary material available at 10.1007/s12028-021-01260-x.
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影响因子：
3.5
作者：
Chou SH;Robertson CS;Participants in the International Multi-disciplinary Consensus Conference on the Multimodality Monitoring
通讯作者：
Participants in the International Multi-disciplinary Consensus Conference on the Multimodality Monitoring
影响因子：
11.2
作者：
Casarotto, Silvia;Comanducci, Angela;Rosanova, Mario;Sarasso, Simone;Fecchio, Matteo;Napolitani, Martino;Pigorini, Andrea;G. Casali, Adenauer;Trimarchi, Pietro D.;Boly, Melanie;Gosseries, Olivia;Bodart, Olivier;Curto, Francesco;Landi, Cristina;Mariotti, Maurizio;Devalle, Guya;Laureys, Steven;Tononi, Giulio;Massimini, Marcello
通讯作者：
Massimini, Marcello
DOI：
10.1016/j.apmr.2015.08.422
发表时间：
2016-03-01
影响因子：
4.3
作者：
Bodien, Yelena G.;Carlowicz, Cecilia A.;Giacino, Joseph T.
通讯作者：
Giacino, Joseph T.
影响因子：
11.2
作者：
Claassen, Jan;Velazquez, Angela;Meyers, Emma;Witsch, Jens;Falo, M. Cristina;Park, Soojin;Agarwal, Sachin;Schmidt, J. Michael;Schiff, Nicholas D.;Sitt, Jacobo D.;Naccache, Lionel;Connolly, E. Sander;Frey, Hans-Peter
通讯作者：
Frey, Hans-Peter
影响因子：
6.5
作者：
Albaeni, Aiham;Chandra-Strobos, Nisha;Eid, Shaker M.
通讯作者：
Eid, Shaker M.