Optimal vaccination strategies - For whom?
Optimal vaccination strategies - For whom?
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DOI：
10.1016/s0025-5564(96)00140-x
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发表时间：
1997-01-15
影响因子：
4.3
通讯作者：
Muller, J
中科院分区：
文献类型：
--
作者：
Muller, J
考虑了一个带有接种的SIRS模型。假设接种疫苗有副作用（为简单起见，这些副作用被建模为由于接种疫苗而生病的概率）。尽量减少疾病的流行符合全体人民的利益；因此，将确定使流行率最小化的疫苗接种率。在第2节中，考虑个人：个人试图将自己的风险降到最低。从这个角度来看，疫苗接种率取决于疾病的流行程度。分析了该系统的分岔，并计算了个体的最佳疫苗接种覆盖率。然后将该覆盖率与总人口的最佳疫苗接种覆盖率进行比较：发现它们在某些参数集上不一致。(C) Elsevier Science Inc., 1997
A SIRS model with vaccination is considered. The vaccination is assumed to have side effects (for simplicity, these side effects are modeled as a probability of becoming ill because of vaccination). It is the interest of the total population to minimize the prevalence of disease; hence, the vaccination rate that minimizes the prevalence will be determined. In Section 2, the individual is considered: an individual tries to minimize his or her own risk. This angle of approach results in a vaccination rate dependent on the prevalence of the disease. The bifurcations of this system are analyzed, and the optimal vaccination coverage for the individual is computed. This coverage is then compared with the optimal vaccination coverage for the total population: it is found that they disagree for some parameter sets. (C) Elsevier Science Inc., 1997