Maternal Dietary Patterns during Pregnancy Are Associated with Child Growth in the First 3 Years of Life
Maternal Dietary Patterns during Pregnancy Are Associated with Child Growth in the First 3 Years of Life
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DOI：
10.3945/jn.116.234336
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发表时间：
2016-11-01
影响因子：
4.2
通讯作者：
Stuebe, Alison M.
中科院分区：
文献类型：
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作者：
Martin, Chantel L.;Siega-Riz, Anna Maria;Stuebe, Alison M.
背景：儿童肥胖是美国的一个主要问题。识别生命早期的危险因素对于预防是必要的。怀孕期间的母亲饮食是胎儿能量的主要来源，可能会影响儿童肥胖的风险。目的：我们前瞻性地研究了怀孕期间母亲的饮食模式对怀孕、感染和营养研究中 389 对母子对儿童出生前 3 岁生长的影响。方法：通过使用基于母亲饮食的潜在类别分析 (LCA) 推导出饮食模式，并在 26-29 周使用食物频率问卷收集数据。妊娠。分别使用线性回归和对数二项式回归评估母亲饮食模式和儿童体重指数 (BMI) 年龄 z 分数与超重或肥胖之间的关联。我们使用线性混合模型来估计与母亲饮食模式相关的儿童生长模式。结果：从 LCA 中识别出三种模式：1）水果、蔬菜、精制谷物、红肉和加工肉类、披萨、炸薯条、糖果、咸味零食和软饮料（潜在类别 1）； 2) 水果、蔬菜、烤鸡肉、全麦面包、低脂乳制品和水（潜在类别 2）； 3) 白面包、红肉和加工肉类、炸鸡、炸薯条和富含维生素 C 的饮料（潜在类别 3）。在粗略分析中，与潜在 2 类饮食相比，潜在 3 类饮食与 1 岁和 3 岁时较高的 BM I-for-age z 评分以及 3 岁时超重或肥胖的风险较高相关。在调整混杂因素后，这些关联无法检测到。我们观察到，在对粗略分析中不明显的混杂因素进行调整后，潜在 3 类饮食与出生时 BM I zscore 之间存在负相关（潜在 3 类与潜在 2-β 类相比：0.41；95% CI：0.79、0.03）。 结论：在这项前瞻性研究中，不健康的母亲饮食模式与幼儿体重模式相关。
Background: Child obesity is a major problem in the United States. Identifying early-life risk factors is necessary for prevention. Maternal diet during pregnancy is a primary source of fetal energy and might influenceirisk of child obesity.Objective: We prospectively investigated the influence of maternal dietary patterns during pregnancy on child growth in the first 3 y of life in 389 mother child pairs from the Pregnancy, Infection, and Nutrition study.Methods: Dietary patterns were derived with the use of latent class analysis (LCA) based on maternal diet, collected with the use of a food-frequency questionnaire at 26-29 wk gestation. Associations between maternal dietary patterns and child body mass index (BMI) for-age zscore and overweight or obesity were assessed with the use of linear regression and log-binomial regression, respectively. We used linear mixed models to estimate childhood growth patterns in relation to maternal dietary patterns.Results: Three patterns were identified from LCA: 1) fruits, vegetables, refined grains, red and processed meats, pizza, french fries, sweets, salty snacks, and soft drinks (latent class 1); 2) fruits, vegetables, baked chicken, whole-wheat bread, low-fat dairy, and water (latent class 2); and 3) white bread, red and processed meats, fried chicken, french fries, and vitamin C rich drinks (latent class 3). In crude analyses, the latent class 3 diet was associated with a higher BM I-for-age z score at 1 and 3 y of age and a higher risk of overweight or obesity at 3 y of age than was the latent class 2 diet. These associations were not detectable after adjustment for confounding factors. We observed an inverse association between the latent class 3 diet and BM I-for-age zscore at birth after adjustment for confounding factors that was not evident in the crude analysis (latent class 3 compared with latent class 2-beta: 0.41; 95% CI: 0.79, 0.03).Conclusion: In this prospective study, a less-healthy maternal dietary pattern was associated with early childhood weight patterns.