Generation of auditory brain stem responses (ABRs). I. Effects of injection of a local anesthetic (procaine HCI) into the trapezoid body of guinea pigs and cat.
Generation of auditory brain stem responses (ABRs). I. Effects of injection of a local anesthetic (procaine HCI) into the trapezoid body of guinea pigs and cat.
复制标题
听觉脑干反应（ABR）的产生。
DOI：
10.1016/0013-4694(83)90259-6
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Starr,A
中科院分区：
文献类型：
--
作者：
Wada,SI;Starr,A
在从腹侧途径将局部麻醉剂（盐酸普鲁卡因）注射到梯形体内之前和之后，记录了麻醉豚鼠的颅骨和非头参考电极之间的听觉脑干电位。除 P1、N1 和 P2 之外的所有组件均受到影响； N2延迟； P3和N3丢失； P4 的持续时间延长，潜伏期缩短； N4 的幅度减弱。所有这些变化都是暂时的，并且发生了组件的恢复。作为刺激强度和速率函数的潜伏期和振幅变化有助于识别改变的成分。这项研究表明梯形体有助于产生从 N2 开始的听觉脑干成分。
Auditory brain stem potentials were recorded between the skull and a non-cephalic reference electrode in anesthetized guinea pigs before and after the injection of a local anesthetic agent (procaine HCI) into the trapezoid body from a ventral approach. All components except P1, N1 and P2 were affected; N2 was delayed; P3 and N3 were lost; P4 was both broadened in duration and shortened in latency; N4 was attenuated in amplitude. All of these changes were temporary and recovery of the components occurred. Identification of the altered components was aided by their latency and amplitude changes as a function of both stimulus intensity and rate. This study implicates the trapezoid body as contributing to the generation of auditory brain stem components beginning with N2.