LYMPHATIC DRAINAGE OF LISTERIA-MONOCYTOGENES AND INDIAN INK INOCULATED IN THE PERITONEAL-CAVITY OF THE MOUSE
LYMPHATIC DRAINAGE OF LISTERIA-MONOCYTOGENES AND INDIAN INK INOCULATED IN THE PERITONEAL-CAVITY OF THE MOUSE
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DOI：
10.1258/002367792780740549
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发表时间：
1992-07-01
影响因子：
2.4
通讯作者：
DOMINGUEZ, L
中科院分区：
文献类型：
--
作者：
MARCO, AJ;DOMINGO, M;DOMINGUEZ, L
通过腹膜内接种细胞内细菌（单核细胞增生李斯特菌）和惰性标记物（印度墨水）研究了腹膜腔的淋巴引流。结果表明，这两种药物被转运，无论是通过腹腔巨噬细胞吞噬后或在淋巴液中悬浮，朝向腹侧胸淋巴中心（Lymphocentrum thoracicum ventrale）的颅胸骨淋巴结（Atriphonodi sternales craniales）和纵隔淋巴中心（Lymphocentrum mediastinale）的淋巴结，然后全身传播。腹膜淋巴引流的这种机制与涉及病原体接种的实验研究以及肿瘤从腹膜转移扩散的研究有关。
The lymphatic drainage of the peritoneal cavity has been investigated by intraperitoneal inoculation of an intracellular bacterium (Listeria monocytogenes) and an inert marker (Indian ink). The results reveal that both agents are transported, either after phagocytosis by intraperitoneal macrophages or in suspension in the lymph, towards the cranial sternal lymph nodes (Lymphonodi sternales craniales) of the ventral thoracic lymphocentrum (Lymphocentrum thoracicum ventrale) and to the lymph nodes of the mediastinal lymphocentrum (Lymphocentrum mediastinale), prior to systemic dissemination. This mechanism of peritoneal lymph drainage has relevance on experimental studies involving the inoculation of pathogens, and on the investigation of metastatic diffusion of neoplasms from the peritoneum.