Interferometric differentiation between resonant coherent anti-Stokes Raman scattering and nonresonant four-wave-mixing processes
Interferometric differentiation between resonant coherent anti-Stokes Raman scattering and nonresonant four-wave-mixing processes
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DOI：
10.1063/1.1829162
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发表时间：
2004-12-06
影响因子：
4
通讯作者：
Boppart, SA
中科院分区：
文献类型：
--
作者：
Marks, DL;Vinegoni, C;Boppart, SA
使用相干反斯托克斯拉曼散射（汽车）来识别生物分子的主要障碍是产生可测量信号所需的照明水平通常也产生来自介质（特别是来自水）的显著非共振背景。我们提出了一种非线性干涉测量的方法来区分反斯托克斯信号的哪些成分是共振和非共振的。该技术利用了共振过程中所涉及的中间态的持久性。该方法适用于大多数现有的脉冲汽车照明方法，并提供了共振汽车的识别。我们通过检查丙酮产生的信号来演示该方法，丙酮具有共振，而水没有。(C)2004年，美国物理学会。
A major impediment to the use of coherent anti-Stokes Raman scattering (CARS) to identify biological molecules is that the illumination levels required to produce a measurable signal often also produce significant nonresonant background from the medium, especially from water. We present a method of nonlinear interferometry to differentiate between which components of the anti-Stokes signal are resonant and nonresonant. The technique takes advantage of the persistence of intermediate states involved in the resonant process. This method is applicable to most existing pulsed CARS illumination methods and provides for identification of resonant CARS. We demonstrate the method by examining the signals produced by acetone, which exhibits resonance, and water, which does not. (C) 2004 American Institute of Physics.