Letters to Dermatology

Letters to Dermatology
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致皮肤科的信

DOI:
10.1159/000017966
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发表时间:
1998
期刊:
影响因子:
3.4
通讯作者:
H. Korting
H. Korting
中科院分区:
医学3区
文献类型:
--
作者:
S. Shephard;N. Schregenberger;R. Dummer;R. Panizzon;H. Tan;Y. Tay;R. Caputo;S. Cambiaghi;A. Brusasco;C. Gelmetti;Y. Kawachi;K. Matsu;H. Sakuraba;F. Otsuka;T. Kobayashi;K. Sakuraoka;M. Iwamoto;S. Kurihara;T. Matsui;T. Kageshita;T. Ishihara;S. Tomiguchi;M. Takahashi;T. Ono;N. Ohtake;M. Setoyama;T. Kanzaki;V. Mahler;C. Antoni;G. Anhalt;H. Koch;K. Peters;B. Manger;J. Kalden;O. Hornstein;S. Hattori;Y. Nagai;S. Tajima;T. Nishikawa;R. Happle;W. Küster;L. Thomas;P. Tranchand;F. Bérard;T. Secchi;C. Colin;G. Moulin;J. Bettinger;M. Gloor;C. Peter;P. Kleesz;J. Fluhr;W. Gehring;E. Tur;S. Brenner;Y. Tokuda;M. Amagai;H. Yaoita;S. Kawachi;T. Ito;I. Matsuyama;S. Tsuchiya;T. Saida;P. Kerkhof;R. Steegers;M. Kuipers;Y. Kaburagi;N. Hatta;S. Kawara;K. Takehara;Y. Yamagami;M. Kohda;S. Mimura;H. Ueki;D. Margolis;J. Weinberg;I. Tangoren;R. Cheney;B. L. Johnson;W. Kempf;G. Burg;J. Bastert;A. Sing;A. Wollenberg;H. Korting

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常规实验室检查显示白色血细胞计数增加17,600/mm 3(中性粒细胞:74%,淋巴细胞:16%,单核细胞:8%,嗜酸性粒细胞:2%,嗜碱性粒细胞:1%),C反应蛋白升高5.9 mg/dl(正常范围,0-0.39)。肝肾功能检查正常。血清IgE升高(830 IU;正常范围,0-400)。在1:2,560(正常范围)检测到抗核抗体的斑点图案!1:40),而没有针对ssDNA、dsDNA、Sm、SS-A/Ro或SS-B/La的抗体。血浆锌水平正常。没有提示胶原蛋白疾病的症状。脓疱的细菌培养物几次仅分离出少量表皮葡萄球菌菌落,表明继发性定植。
Routine laboratory examinations showed an increased white blood cell count of 17,600/mm 3 (neutrophils: 74%, lymphocytes: 16%, monocytes: 8%, eosinophils: 2%, basophils: 1%) and elevated C-reactive protein of 5.9 mg/dl (normal range, 0–0.39). Liver and renal function tests were normal. Serum IgE was increased (830 IU; normal range, 0–400). A speckled pattern of antinuclear antibody was detected at 1: 2,560 (normal range ! 1: 40) without antibodies to ssDNA, dsDNA, Sm, SS-A/Ro or SS-B/La. The plasma zinc levels were normal. There were no symptoms suggestive of collagen diseases. Bacterial cultures from the pustules isolated only a small number of colonies of Staphylococcus epidermidis on several occasions, indicating a secondary colonization.