A 2-PHASE FINITE-ELEMENT MODEL OF THE DIASTOLIC LEFT-VENTRICLE
A 2-PHASE FINITE-ELEMENT MODEL OF THE DIASTOLIC LEFT-VENTRICLE
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DOI：
10.1016/0021-9290(91)90286-v
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发表时间：
1991-01-01
影响因子：
2.4
通讯作者：
HEETHAAR, RM
中科院分区：
文献类型：
--
作者：
HUYGHE, JM;VANCAMPEN, DH;HEETHAAR, RM
建立了被动左心室的多孔介质有限元模型。该模型是轴对称的，并允许有限的变形，包括扭转对称轴。模型采用各向异性准线性粘弹性本构关系。该模型考虑了心肌壁纤维方向的变化。在被动填充期间，对于从顶点到基部观察的观察者，顶点相对于基部沿顺时针方向旋转。在0-3 kPa的脑室内压范围内，所有结节的旋转角均保持在0.1rad以下。心肌组织的舒张粘弹性被证明可以减少预负荷引起的肌节拉伸的透壁差异，并在未加载的心室壁中产生残余应力，这与心脏切开时观察到的张开角度一致。结果表明，随着冠状动脉内血容量的增加，心室模型变硬。在给定的左心室容量下，当冠状动脉内血容量从9 ml（100 g）-1左心室增加到14 ml（100 g）-1左心室时，左心室压力从1.5 kPa增加到2.0 kPa。
A porous medium finite element model of the passive left ventricle is presented. The model is axisymmetric and allows for finite deformation, including torsion about the axis of symmetry. An anisotropic quasi-linear viscoelastic constitutive relation is implemented in the model. The model accounts for changing fibre orientation across the myocardial wall. During passive filling, the apex rotates in a clockwise direction relative to the base for an observer looking from apex to base. Within an intraventricular pressure range of 0-3 kPa the rotation angle of all nodes remained below 0.1 rad. Diastolic viscoelasticity of myocardial tissue is shown to reduce transmural differences of preload-induced sarcomere stretch and to generate residual stresses in an unloaded ventricular wall, consistent with the observation of opening angles seen when the heart is slit open. It is shown that the ventricular model stiffens following an increase of the intracoronary blood volume. At a given left ventricular volume, left ventricular pressure increases from 1.5 to 2.0 kPa when raising the intracoronary blood volume from 9 to 14 ml (100 g)-1 left ventricle.