Environmental Pollutants: Effects on the Immune System and Resistance to Infectious Disease
Environmental Pollutants: Effects on the Immune System and Resistance to Infectious Disease
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环境污染物：对免疫系统和传染病抵抗力的影响
DOI：
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发表时间：
1981
期刊：
影响因子：
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通讯作者：
L. D. Caren
中科院分区：
文献类型：
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作者：
L. D. Caren
免疫系统是一个复杂的相互关联的反应，它保护动物免受外来物质的入侵。许多环境物质，如金属，有机农药和气态污染物，扰乱免疫反应，增加对传染病的易感性。需要进行大量的系统研究。这些研究应包括在大量动物身上进行长期低剂量实验，使用更多种类的传染媒介研究感染抵抗力受损的情况，研究胎儿和新生儿接触污染的影响，以及研究一旦观察到影响后抵抗力受损的机制。审查了26篇参考文献。
The immune system is a complex of interrelated reactions, which protects animals from invasion by foreign substances. Many environmental substances, such as metals, organic pesticides, and gaseous pollutants, perturb the immune response and increase susceptibility to infectious disease. There is a need for a large number of systematic studies. They should include long-term, low dose experiments on large numbers of animals, studies of impaired resistance to infection using a greater variety of infectious agents, studies of the effects of fetal and neonatal pollution exposure, and studies of the mechanism of impaired resistance once an effect is observed. 26 references reviewed.