Proteome analysis of resting human neutrophils

Proteome analysis of resting human neutrophils
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DOI:
10.2174/092986606776819529
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发表时间:
2006-01-01
影响因子:
1.6
通讯作者:
Fontes, Wagner
Fontes, Wagner
中科院分区:
生物学4区
文献类型:
--
作者:
de Souza Castro, Mariana;Monsores de Sa, Natan;Fontes, Wagner

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Neutrophils constitute the first line of host defense against pathogens. In the present study 2-D gel electrophoresis-mass spectrometry technology was employed to analyze the human resting neutrophils proteome. One hundred and two conserved spots were subjected to peptide mass fingerprinting, yielding 22 identifications. Among the identified proteins, nine are related to the inflammatory process, two polypeptides are assigned to metabolic functions and five are classified as structural.