Right ventricular electrocardiographic leads for detection of Brugada syndrome in sudden unexplained death syndrome survivors and their relatives
Right ventricular electrocardiographic leads for detection of Brugada syndrome in sudden unexplained death syndrome survivors and their relatives
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DOI：
10.1002/clc.4960241205
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发表时间：
2001-12-01
影响因子：
2.7
通讯作者：
Tungsanga, K
中科院分区：
文献类型：
--
作者：
Sangwatanaroj, S;Prechawat, S;Tungsanga, K
背景资料：不明原因猝死综合征（Sudden Unexplained Death Syndrome，简称SUDS）是一种发生在东南亚年轻人身上的猝死综合征，通常发生在没有任何结构性死亡原因的年轻人身上。许多SUDS幸存者的心电图（ECG）显示RSR'和V-1至V-3导联ST段抬高的证据，这与Brugada综合征的ECG模式相似。然而，在许多情况下，短暂的正常化的心电图不作出诊断与标准的12导联ECOMENT.Hypothesis：为了克服这个问题，我们利用新的右心室心电图导致检测Brugada综合征SUDS survivors.Methods：该主题是一个泰国男性患者谁提出了一个SUDS样晕厥发作。结果：复苏后标准12导联心电图未显示Brugada综合征的诊断特征。然而，在较高的肋间隙导联V-1至V-3处可检测到Brugada综合征典型的RSR和ST段抬高的ECG模式。我们观察到类似的结果，在其他10 SUDS幸存者和23名健康的家庭members.Conclusions 4：我们的数据表明，这些新的右心室导联心电图可能有助于检测Brugada综合征的SUDS幸存者及其亲属。
Background: Sudden unexplained death syndrome (SUDS) is a sudden death syndrome in previously healthy Southeast Asian young adults without any structural causes of death. Many SUDS survivors show electrocardiographic (ECG) evidence of RSR' and ST elevation in leads V-1 to V-3, which is similar to the ECG pattern in Brugada syndrome. However, in many cases transient normalization of the ECG does not make diagnosis with standard 12-lead ECG possible.Hypothesis: To overcome this problem, we utilized the new right ventricular ECG leads to detect the Brugada syndrome in SUDS survivors.Methods: The subject was a Thai male patient who presented with a SUDS-like syncopal attack. He had cardiac arrest due to idiopathic ventricular fibrillation.Results: Post-resuscitation standard 12-lead ECG showed no diagnostic features of Brugada syndrome. However, ECG patterns of RSR' and ST elevations typical for Brugada syndrome could be detected at the higher intercostal space leads V-1 to V-3. We observed similar findings in 2 of the other 10 SUDS survivors and 4 of 23 healthy family members.Conclusions: Our data suggest that these new right ventricular leads ECG may be helpful in detecting Brugada syndrome in SUDS survivors and their relatives.