Copper-Catalyzed Decarboxylative Disulfonylation of Alkynyl Carboxylic Acids with Sulfinic Acids
Copper-Catalyzed Decarboxylative Disulfonylation of Alkynyl Carboxylic Acids with Sulfinic Acids
复制标题
铜催化炔基羧酸与亚磺酸的脱羧二磺酰化反应
DOI：
10.1021/acs.orglett.7b03922
复制
发表时间：
2018-01-19
期刊：
影响因子：
5.2
通讯作者：
Li, Ya-Min
中科院分区：
文献类型：
--
作者：
Fu, Hong;Shang, Jia-Q;Li, Ya-Min
研究了水溶液中铜催化炔基羧酸与亚磺酸的脱羧二磺酰化反应。该反应提供了一种直接和实用的方法来获得（E）-1，2-二磺酰基乙烯，这是合成有机化学中的重要构件，并且表现出良好的官能团耐受性和优异的立体选择性。提出了一种可能的转换机制。
A copper-catalyzed decarboxylative disulfonylation of alkynyl carboxylic acids with sulfinic acids in aqueous solution has been developed. The reaction provides a straightforward and practical access to (E)-1,2-disulfonylethenes, which are important building blocks in synthetic organic chemistry, and exhibits a good functional group tolerance and excellent stereoselectivity. A possible mechanism for the transformation is proposed.