Bacterial outer membranes as model systems
Bacterial outer membranes as model systems
复制标题
细菌外膜作为模型系统
DOI：
10.1016/0014-5793(88)80147-9
复制
发表时间：
1988
期刊：
影响因子：
3.5
通讯作者：
H. Perkins
中科院分区：
文献类型：
--
作者：
H. Perkins
This book is divided into three parts. The first on Gene and Gene Expression and the second on Membrane Proteins: Structure and Function relate fairly strictly to the title of the whole book and cover 225 of the total 417 pages of text. As Inouye states in his preface, the seven chapters included in Part III, Interaction with Other Systems, describe structural and functional aspects of bacterial cell surfaces. The book as a whole is extremely well presented and as free from irritating typographical errors as one could reasonably hope. One author, Rosenbusch, acknowledges help from various people who “successfully rescued the manuscript from the claws of a word predator”, a comment that could fairly be applied to the whole book. Many authors have produced excellent diagrammatic material that enables the reader to assimilate more easily the complex ideas being presented. A list of the chapter titles contained in the first two parts shows that each topic has been approached from many angles and that there is a great deal of overlap of ideas and information. Thus, Transcriptional Control of Gene Expression: Osmoregulation of Porin Protein Synthesis (Ramakrishnan, Comeau, Ikenaka and Inouye) is followed by Posttranscriptional Regulation of Gene Expression (Green and Inouye) and Posttranslational Modification and Processing of Membrane Proteins in Bacteria (Wu). Inevitably there is much in common between some parts of these chapters and the ones entitled Export and Localization of Escherichia cofi Envelope Proteins (Bankaitis, Altman and Emr), Structure and Functions of the Signal Peptide (Pollett and Inouye) and Assembly of Membrane Proteins (Mizushima). Many a reviewer has had cause to describe a particular work as ‘The Bible’for a specialist field, and there is no doubt that the present compilation could fairly claim to be an Authorized Version (1987) in regard to the topics just mentioned. Indeed, the resemblance to the Bible does not end there. Just as that multiauthor document is notorious for enabling all sorts of conflicting views to be held as a consequence of reading it, so the present text permits readers to develop beliefs and views of their own within the plethora of well-documented information provided. Indeed, the parallel to the Synoptic Gospels is even stronger; the same events are described in various ways that offer different highlights and allow for different and additional shafts of understanding.Many of these chapters conclude with passages indicating that, for all that has been discovered in the last 15-20 years, there is a level of understanding of the vectorial processes involved in the manufacture and siting of membrane proteins that has not yet been achieved. For instance, Bankaitis, Altman and Emr remark that “protein export in E. coli is a dauntingly complex series of events, the resolution of which is of interest not only to the basic scientist, but also to the applied scientist who wishes to engineer secretion of proteins by this organism”. For people in both of these categories the present volume would be an invaluable companion, providing vital information and provoking thought.
