EFFECTS OF HIGH-INTENSITY STRENGTH TRAINING ON MULTIPLE RISK-FACTORS FOR OSTEOPOROTIC FRACTURES - A RANDOMIZED CONTROLLED TRIAL
EFFECTS OF HIGH-INTENSITY STRENGTH TRAINING ON MULTIPLE RISK-FACTORS FOR OSTEOPOROTIC FRACTURES - A RANDOMIZED CONTROLLED TRIAL
复制标题
DOI：
10.1001/jama.272.24.1909
复制
发表时间：
1994-12-28
影响因子：
120.7
通讯作者：
EVANS, WJ
中科院分区：
文献类型：
--
作者：
NELSON, ME;FIATARONE, MA;EVANS, WJ
客观。-为了确定绝经后妇女如何通过高强度力量训练来改变骨质疏松性骨折的多种危险因素。为期1年的随机对照试验。塔夫茨大学运动实验室，波士顿，马萨诸塞州人口。40名绝经后白色女性，年龄在50至70岁之间，参加了这项研究; 39名女性完成了这项研究。受试者久坐不动，雌激素耗尽。每周2天进行高强度力量训练，使用五种不同的运动（n=20）与未治疗的对照组（n=19）。主要结果指标。-双能X线骨密度测定法用于骨状态，一次重复最大肌力，24小时尿肌酐用于肌肉质量，向后串联行走用于动态平衡。股骨颈骨密度和腰椎骨密度增加0.005+/-0.039 g/cm（2）（0.9%+/-4.5%）（平均值+/-SD）和0.009+/-0.033 g/cm（2）（1.0%+/-3.6%），在力量训练的女性中，下降了-0.022+/-0.035 g/cm（2）（-2.5%+/-3.8%）和-0.019+/-0.035 g/cm（2）（-1.8%+/-3.5%）（P= 0.02和0.04）。接受力量训练的女性的全身骨矿物质含量保持不变（+2.0+/-68 g; 0.0%+/-3.0%），而对照组则呈下降趋势（-33+77 g; -1.2%+/-3.4%，P= 0.12）。肌肉质量、肌肉力量和动态平衡在力量训练的女性中增加，而在对照组中减少（P= 0.03至0.05）。
Objective.-To determine how multiple risk factors for osteoporotic fractures could be modified by high-intensity strength training exercises in postmenopausal women.Design.-Randomized controlled trial of 1-year duration.Setting.-Exercise laboratory at Tufts University, Boston, Mass.Population.-Forty postmenopausal white women, 50 to 70 years of age, participated in the study; 39 women completed the study. The subjects were sedentary and estrogen-deplete.Interventions.-High-intensity strength training exercises 2 days per week using five different exercises (n=20) vs untreated controls (n=19).Main Outcome Measures.-Dual-energy x-ray absorptiometry for bone status, one repetition maximum for muscle strength, 24-hour urinary creatinine for muscle mass, and backward tandem walk for dynamic balance.Results.-Femoral neck bone mineral density and lumbar spine bone mineral density increased by 0.005+/-0.039 g/cm(2) (0.9%+/-4.5%) (mean+/-SD) and 0.009+/-0.033 g/cm(2) (1.0%+/-3.6%), respectively, in the strength-trained women and decreased by -0.022+/-0.035 g/cm(2) (-2.5%+/-3.8%) and -0.019+/-0.035 g/cm(2) (-1.8%+/-3.5%), respectively, in the controls (P=.02 and .04). Total body bone mineral content was preserved in the strength-trained women (+2.0+/-68 g; 0.0%+/-3.0%) and tended to decrease in the controls (-33+77 g; -1.2%+/-3.4%, P=.12). Muscle mass, muscle strength, and dynamic balance increased in the strength-trained women and decreased in the controls (P=.03 to