ASSOCIATION OF FASTING INSULIN WITH BLOOD-PRESSURE AND LIPIDS IN YOUNG-ADULTS - THE CARDIA STUDY
ASSOCIATION OF FASTING INSULIN WITH BLOOD-PRESSURE AND LIPIDS IN YOUNG-ADULTS - THE CARDIA STUDY
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DOI：
10.1161/01.atv.10.3.430
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发表时间：
1990-05-01
期刊：
影响因子：
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通讯作者：
OBERMAN, A
中科院分区：
文献类型：
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作者：
MANOLIO, TA;SAVAGE, PJ;OBERMAN, A
胰岛素与心血管疾病（CVD）的相关性可能部分由胰岛素与CVD风险因素（特别是血压和血脂）的相关性介导。在CARDIA研究中，对4576名黑人和白色年轻人进行了研究。空腹胰岛素水平与收缩压呈单因素相关（r=0.16），舒张压（r=0.13），甘油三酯（r=0.27），总胆固醇（r=0.10），高密度脂蛋白（HDL）胆固醇（r=-0.25）和低密度脂蛋白（LDL）胆固醇（r=0.14），并与年龄、性别、种族、血糖、体重指数、酒精摄入量、吸烟、体育活动和跑步机持续时间（所有p）
The association of insulin with cardiovascular disease (CVD) may be mediated in part by the associations of insulin with CVD risk factors, particularly blood pressure and serum lipids. These associations were examined in 4576 black and white young adults in the CARDIA Study. Fasting insulin level was correlated in univariate analysis with systolic blood pressure (r=0.16), diastolic blood pressure (r=0.13), triglycerides (r=0.27), total cholesterol (r=0.10), high density lipoprotein (HDL) cholesterol (r=-0.25), and low density lipoprotein (LDL) cholesterol (r=0.14), and with age, sex, race, glucose, body mass index, alcohol intake, cigarette use, physical activity, and treadmill duration (all p