The effect of acupuncture on pain, dyspareunia, and quality of life in Brazilian women with endometriosis: A randomized clinical trial
The effect of acupuncture on pain, dyspareunia, and quality of life in Brazilian women with endometriosis: A randomized clinical trial
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DOI：
10.1016/j.ctcp.2016.09.006
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发表时间：
2016-11-01
影响因子：
3
通讯作者：
Sperandio, Fabiana Flores
中科院分区：
文献类型：
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作者：
de Sousa, Tatiane Regina;de Souza, Bruna Cruz;Sperandio, Fabiana Flores
子宫内膜异位症（Endometriosis）是一种以子宫内膜组织出现在子宫腔外为特征的疾病，其病因尚不清楚，但最被接受的理论是逆行性子宫内膜异位症（retrograde mesntruacao），即部分经血返回体内而不是被排出。目的：本研究的目的是基于随机临床试验，观察针刺方案对慢性盆腔疼痛、性交困难、方法：为了测试针灸的疗效，我们选择了42名在巴西圣卡塔里纳的弗洛里亚诺波利斯大学医院等待接受视频腹腔镜检查的妇女。这些妇女被分为两个样本组。第一组接受了针灸的实验性治疗，另一组接受了安慰剂治疗，针插入距离能量点3厘米。每组进行5次治疗，平均持续40分钟。使用临床试验管理系统软件进行随机化，分配顺序由实验室助理执行，并隐藏在负责收集信息的项目团队中。为了监测这种干预的效果，我们使用了视觉模拟量表（VAS）和子宫内膜异位症健康状况30（EHP-30）子宫内膜异位症的生活质量问卷。在治疗前、治疗后和治疗后2个月3个时间点测量变量。结果：用SAS软件9.1.3版进行方差分析。在分析的两组中均观察到慢性盆腔疼痛和性交困难的VAS评分降低。然而，治疗后2个月，只有实验组的结果保持不变。关于生活质量，我们观察到所有分析变量的改善，尽管这些仅在实验组中具有统计学意义。相比之下，不孕不育的变量没有达到显着性在任何group.Conclusions：我们的结论是，针灸赋予有益的和持久的影响，即使2个月后治疗，所证明的变量studied.Registered在巴西临床试验注册处（REBEC）的识别码RBR-7 cfctd。(C)2016爱思唯尔有限公司版权所有
Endometriosis is a disease characterized by the presence of endometrial tissue outside the cavity of the uterus, its cause is still unknown, but the most accepted theory is the retrograde mesntruacao, which states that part of the menstrual blood returns to the body instead of being eliminated.Objectives: The aim of this study, based on a randomized clinical trial, was to observe the effects of an acupuncture protocol on chronic pelvic pain, dyspareunia, and quality of life in women with endometriosis.Methods: To test the efficacy of acupuncture, we selected 42 women who were on the waiting list to undergo a videolaparoscopy at the University Hospital of Florianopolis, Santa Catarina, Brazil. These women were divided into two sample groups. The first received the experimental treatment of acupuncture, and the other received placebo therapy, for which the needles were inserted 3 cm apart from the points of energy. Each group underwent five treatment sessions lasting on average 40 min. Randomization was carried out using Clinical Trial Management System software, and the allocation sequence was performed by a laboratory assistant and hidden to the team conducting the project, which was responsible for collecting the information. To monitor the effects of this intervention, we used the visual analogue scale (VAS) and the quality-of-life questionnaire for Endometriosis Health Profile 30 (EHP-30) endometriosis. Variables were measured at three time points: pre-therapy, post-therapy, and 2 months after therapy.Results: The results were analysed with SAS software version 9.1.3 using analysis of variance. A decrease in VAS scores for chronic pelvic pain and dyspareunia was observed in both groups analysed. However, 2 months after therapy, the results were maintained only in the experimental group. Regarding quality of life, we observed an improvement in all variables analysed, although these were statistically significant only in the experimental group. In contrast, the variable for infertility did not reach significance in either group.Conclusions: We concluded that acupuncture confers beneficial and long-lasting effects, even 2 months after therapy, as demonstrated by the variables studied.Registered in the Brazilian Clinical Trials Registry (REBEC) with the identification codeRBR-7cfctd. (C) 2016 Elsevier Ltd. All rights reserved.