Synthesis of new hyodeoxycholic acid thiosemicarbazone derivatives under solvent-free conditions using microwave

Synthesis of new hyodeoxycholic acid thiosemicarbazone derivatives under solvent-free conditions using microwave
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DOI:
10.1016/j.cclet.2010.10.020
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发表时间:
2011-04
影响因子:
9.1
通讯作者:
Zhichuan Shi;Zhigang Zhao;Xingli Liu;Yu Chen
Zhichuan Shi;Zhigang Zhao;Xingli Liu;Yu Chen
中科院分区:
化学1区
文献类型:
--
作者:
Zhichuan Shi;Zhigang Zhao;Xingli Liu;Yu Chen

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An efficient and simple method for synthesis of new hyodeoxycholic acid thiosemicarbazone derivatives under solvent-free conditions using microwave has been developed. Its main advantages are short reaction times, good conversions and the environmentally friendly nature of the process. The preliminary results indicate that some of these compounds possess inhibitory effects against E. coli.