VALUE OF REPEAT LUMBAR PUNCTURE IN DIFFERENTIAL DIAGNOSIS OF MENINGITIS
VALUE OF REPEAT LUMBAR PUNCTURE IN DIFFERENTIAL DIAGNOSIS OF MENINGITIS
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DOI：
10.1056/nejm197309132891108
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发表时间：
1973-01-01
影响因子：
158.5
通讯作者：
SHACKELFORD, PG
中科院分区：
文献类型：
--
作者：
FEIGIN, RD;SHACKELFORD, PG
细菌性脑膜炎和无菌性脑膜炎的症状和体征可能相似，因此通常不能在临床上做出鉴别诊断。鉴别细菌性脑膜炎和无菌性脑膜炎的一个关键决定因素是在患者初次检查时对脑脊液的评估。当细胞增多症超过每立方毫米1000个细胞并且主要由多形核白细胞组成时，细菌性脑膜炎的怀疑增加。此外，如果脑脊液葡萄糖低于每100毫升40毫克，或低于同时获得的血糖的66%，并且与存在相关。
THE symptoms and signs of bacterial and aseptic meningitis may be similar, and thus the differential diagnosis usually cannot be made on clinical grounds. A critical determinant in differentiating bacterial from aseptic meningitis is evaluation of the cerebrospinal fluid at the time of initial examination of the patient. When pleocytosis exceeds 1000 cells per cubic millimeter and consists predominantly of polymorphonuclear leukocytes, suspicion of bacterial meningitis is heightened. If, in addition, the cerebrospinal-fluid glucose is less than 40 mg per 100 ml, or less than 66 per cent of a simultaneously obtained blood glucose, and is associated with the presence . . .