A case of Churg-Strauss syndrome: flow cytometric analysis of the surface activation markers of peripheral eosinophils.
A case of Churg-Strauss syndrome: flow cytometric analysis of the surface activation markers of peripheral eosinophils.
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DOI：
10.2340/00015555-1384
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发表时间：
2013
影响因子：
3.6
通讯作者：
Kyoko Nakahigashi;A. Otsuka;Y. Miyachi;K. Kabashima;M. Tanioka
中科院分区：
文献类型：
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作者：
Kyoko Nakahigashi;A. Otsuka;Y. Miyachi;K. Kabashima;M. Tanioka
© 2013作者。doi：10.2340/00015555-1384 Journal Compilation © 2013 Acta Dermato-Venereologica. ISSN 0001-5555 Churg-Strauss综合征（CSS）是一种复杂的多器官疾病（1）。美国流变学学会提出了6项CSS分类标准，满足4项标准可诊断CSS（2）。这些标准包括哮喘、嗜酸性粒细胞增多、单神经病或多神经病、肺浸润、鼻窦异常和血管外嗜酸性粒细胞。在40%的CSS患者中经常观察到皮肤表现。我们在此报告一个CSS的病例，以流式细胞术分析外周嗜酸性粒细胞，呈现不典型的皮肤及皮下表现。
© 2013 The Authors. doi: 10.2340/00015555-1384 Journal Compilation © 2013 Acta Dermato-Venereologica. ISSN 0001-5555 Churg–Strauss syndrome (CSS) is a complex multiple organ disease (1). The American College of Rheumatology has proposed 6 criteria for CSS classification, with the fulfilment of 4 criteria making a diagnosis of CSS (2). These criteria include asthma, eosinophilia, mononeuropathy or polyneuropathy, pulmonary infiltrates, paranasal sinus abnormality and extravascular eosinophils. Cutaneous manifestations are frequently observed in 40% of CSS patients. We report here a case of CSS presenting atypical cutaneous and subcutaneous manifestations of CSS with flow cytometric analysis of the peripheral eosinophils.