EPIDEMIOLOGY OF LARGE-BOWEL CANCER
EPIDEMIOLOGY OF LARGE-BOWEL CANCER
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DOI：
10.1007/bf01789199
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发表时间：
1991-09-01
影响因子：
2.6
通讯作者：
DOZOIS, RR
中科院分区：
文献类型：
--
作者：
LEVIN, KE;DOZOIS, RR
流行病学研究的结果为大肠癌的病因学提供了见解。结直肠癌的发病率在世界不同地区和特定国家的不同区域存在明显差异。对流动人口的研究揭示了环境因素，特别是饮食因素在结直肠癌病因中的作用。遗传因素和炎症性肠病也使某些人面临更高的风险。久坐不动的生活方式、胆囊切除和输尿管乙状结肠吻合术也可能增加患结肠癌的风险。
Results from epidemiologic studies have provided insights into the etiology of large bowel cancer. Markedly diverse incidences of colorectal cancer exist in various parts of the world and within different regions of a given country. Studies of migrant populations have revealed a role for environmental factors, particularly dietary, in the etiology of colorectal cancers. Genetic factors and inflammatory bowel disease also place certain individuals at increased risk. Sedentary lifestyle, cholecystectomy, and ureterosigmoidostomy may also increase the risk of developing large bowel cancer.