On sex differences in optimal immunity

On sex differences in optimal immunity
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DOI:
10.1016/j.tree.2006.12.004
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发表时间:
2007-03-01
影响因子:
16.8
通讯作者:
Forbes, Mark R.
Forbes, Mark R.
中科院分区:
生物学1区
文献类型:
--
作者:
Forbes, Mark R.

文献摘要

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免疫中的性别偏见引起了人们的极大兴趣,因为它们可能与生殖策略中的性别差异有关。研究人员经常认为,男性在免疫力方面的投入应该比女性少。在最近的一篇论文中,Stoehr和Kokko挑战了这种合理证实的“易感男性”观点。他们的模型,以及Medley的另一个模型,有助于强调相关的测试,这些测试可以解释免疫力物种内变异的其他重要来源及其对寄生虫的重要性。
Sex biases in immunity have generated much interest because of their possible connection with sex differences in reproductive strategies. Researchers have often argued that males should invest less in immunity than should females. In a recent paper, Stoehr and Kokko challenge this reasonably substantiated view of 'susceptible males'. Their model, and another by Medley, helps highlight relevant tests that could explain other important sources of within-species variation in immunity and its importance to parasitism.