Sex dependent effects of silver nanoparticles on the zebrafish gut microbiota
Sex dependent effects of silver nanoparticles on the zebrafish gut microbiota
复制标题
银纳米颗粒对斑马鱼肠道微生物群的性别依赖性影响
DOI：
10.1039/c7en00740j
复制
发表时间：
2018-03-01
影响因子：
7.3
通讯作者：
Pei, De-Sheng
中科院分区：
文献类型：
--
作者：
Ma, Yanbo;Song, Liyan;Pei, De-Sheng
Silver nanoparticles (AgNPs), the most prevalent commercial nanomaterial products, are widely released into the environment. AgNPs are toxic to various aquatic organisms, but their influence on the aquatic organism's gut microbiota remains unknown. Here, we characterized the bacterial communities in the guts of adult zebrafish treated with AgNPs (10, 33 or 100 mu g L-1 ) for 35 days and also measured the concentration of AgNPs in the zebrafish digestive tract. As expected, dose dependence of AgNP accumulation was observed in the digestive tract, accompanied by decreased overall microbial richness and diversity. To our surprise, however, the effects of the AgNP treatment on the gut microbiota of male and female fish were not the same; furthermore, AgNPs significantly altered the relative composition of the bacterial species in the community harbored in male zebrafish but not in females. This research investigates and compares zebrafish intestinal microbiota after AgNP exposure, pointing to the potential health risk to aquatic organisms from alteration of gut microbiota.
