Transposition protein of Tn3: identification and characterisation of an essential represser-controlled gene product
Transposition protein of Tn3: identification and characterisation of an essential represser-controlled gene product
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Tn3 转座蛋白：必需阻遏物控制基因产物的鉴定和表征
DOI：
10.1038/282801a0
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发表时间：
1979
期刊：
影响因子：
64.8
通讯作者：
Stanley N Cohen
中科院分区：
文献类型：
--
作者：
J. Chou;P. Lemaux;M. Casadaban;Stanley N Cohen
Tn3元件内转录和翻译信号控制lac基因表达的融合已被用于鉴定和鉴定Tn3编码的转座酶(TNP)肽，其分子量为100,000，对于转座是必不可少的。指定该产物的基因受Tn3抑制蛋白的调控，是包括抑制基因的双向遗传单位的一部分。
Fusions that bring lac gene expression under the control of transcriptional and translational signals within the Tn3 element have been used to identify and characterise a Tn3-encoded ‘transposase’ (Tnp) peptide of MW 100,000 essential f or transposition. The gene specifying this product is regulated by the Tn3 repressor protein and is part of a bidirectional genetic unit that includes the repressor gene.