Oxygen-enhanced MR imaging: Correlation with postsurgical lung function in patients with lung cancer
Oxygen-enhanced MR imaging: Correlation with postsurgical lung function in patients with lung cancer
复制标题
DOI：
10.1148/radiol.2361040005
复制
发表时间：
2005-08-01
期刊：
影响因子：
19.7
通讯作者：
Sugimura, K
中科院分区：
文献类型：
--
作者：
Ohno, Y;Hatabu, H;Sugimura, K
目的：与计算机断层扫描 (CT) 和闪烁扫描的定量和定性结果相比，前瞻性地确定氧增强磁共振 (MR) 成像评估的肺功能是否与肺癌患者术后肺功能相关。 材料和方法：研究获得机构审查委员会批准，并获得患者知情同意。连续 30 名考虑肺切除候选者（16 名男性和 14 名女性，年龄 44-81 岁；平均年龄 65 岁）的患者接受了氧增强 MR 成像、CT、灌注闪烁扫描和 1 秒用力呼气量 (FEV1) 测量。呼吸同步反转恢复半傅里叶单次涡轮自旋回波磁共振序列用于数据采集。通过氧气增强 MR 成像（FEV1MR、CT 定量评估 (FEV1Quant)、CT 定性评估 (FEV1Qual) 和灌注闪烁扫描 (FEV1PS)）确定术后肺功能（术后 FEV1）与实际术后 FEV1 的相关性，并通过 Bland-Altman 分析确定每个的一致性限制。 结果：术后 FEV1MR 与实际值之间的相关性术后 FEV1 值非常好（r(2) = 0.81，P
PURPOSE: To prospectively determine if lung function as assessed with oxygen-enhanced magnetic resonance (MR) imaging correlates with postsurgical lung function in patients with lung cancer, as compared with quantitative and qualitative findings of computed tomography (CT) and scintigraphy.MATERIALS AND METHODS: Study received institutional review board approval, and informed patient consent was obtained. Thirty consecutive patients (16 men and 14 women, aged 44-81 years; mean age, 65 years) considered candidates for lung resection underwent oxygen-enhanced MR imaging, CT, perfusion scintigraphy, and measurement of forced expiratory volume in 1 second (FEV1). A respiratory-synchronized inversion-recovery half-Fourier single-shot turbo spin-echo MR sequence was used for data acquisition. Correlation of postsurgical lung function (postsurgical FEV1) as determined with oxygen-enhanced MR imaging (FEV1MR, quantitative assessment with CT (FEV1Quant), qualitative assessment with CT (FEV1Qual), and perfusion scintigraphy (FEV1PS) was conducted with actual postsurgical FEV1 and the limits of agreement of each were determined with Bland-Altman analysis.RESULTS: Correlation between postsurgical FEV1MR and actual postsurgical FEV1 values was excellent (r(2) = 0.81, P