COLOR-VISION LOSS IN WORKERS EXPOSED TO ELEMENTAL MERCURY-VAPOR
COLOR-VISION LOSS IN WORKERS EXPOSED TO ELEMENTAL MERCURY-VAPOR
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DOI：
10.1016/0378-4274(95)03317-3
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发表时间：
1995-05-01
影响因子：
3.5
通讯作者：
SEGHIZZI, P
中科院分区：
文献类型：
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作者：
CAVALLERI, A;BELOTTI, L;SEGHIZZI, P
我们评估了33名接触元素汞（Hg）蒸气的工人和33名性别、年龄、饮酒和吸烟相匹配的参考者的色觉。结果表示为颜色混淆指数（CCI）。在工人尿汞排泄量（HgU）范围从28至287微克/克肌酐。在工人中观察到亚临床色觉丧失，主要在蓝黄色范围内。HgU与CCI相关（r = 0.488，P < 0.01），提示汞对慢性乙型肝炎的影响与暴露有关。在工人的HgU超过50微克/克肌酐，平均CCI显着增加相比，匹配的参考。结果表明，暴露于元素汞诱导HgU值超过50微克/克肌酐可以诱导剂量相关的色觉丧失。
We evaluated colour vision in 33 workers exposed to elemental mercury (Hg) vapour and in 33 referents matched for sex, age, alcohol consumption and cigarette smoking. The results were expressed as colour confusion index (CCI). In the workers urinary excretion of Hg (HgU) ranged from 28 to 287 mu g/g creatinine. Subclinical colour vision loss, mainly in the blue-yellow range, was observed in the workers. This effect was related to exposure, as indicated by the correlation between HgU and CCI (r = 0.488, P < 0.01). In the workers whose HgU exceeded 50 mu g/g creatinine, mean CCI was significantly increased compared to the matched referents. The results suggest that exposure to elemental Hg inducing HgU values exceeding 50 mu g/g creatinine can induce a dose-related colour vision loss.