Genome re-annotation: a wiki solution?

Genome re-annotation: a wiki solution?
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基因组再保管:Wiki解决方案?

DOI:
10.1186/gb-2007-8-1-102
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发表时间:
2007
期刊:
影响因子:
12.3
通讯作者:
--
中科院分区:
生物学1区
文献类型:
--
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基因组注释目前往往呈现为一种静态的快照。常规的重新注释(或许可以使用维基软件)会有所帮助。 大多数基因组的注释随着时间推移会变得过时,部分原因是我们对基因组的了解不断提高,部分原因是生物信息学软件的改进。不幸的是,注释很少(即便有过)得到更新,而且支持常规重新注释的资源稀缺。维基软件(它能让许多科学家编辑每个基因组的注释)提供了一种可能的解决方案。
Genome annotation currently tends to represent a static snapshot. Routine re-annotation, perhaps using wiki software, would help. The annotation of most genomes becomes outdated over time, owing in part to our ever-improving knowledge of genomes and in part to improvements in bioinformatics software. Unfortunately, annotation is rarely if ever updated and resources to support routine reannotation are scarce. Wiki software, which would allow many scientists to edit each genome's annotation, offers one possible solution.