What Are We Missing Here? Brain Imaging Evidence for Higher Cognitive Functions in Primary Visual Cortex V1
What Are We Missing Here? Brain Imaging Evidence for Higher Cognitive Functions in Primary Visual Cortex V1
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DOI：
10.1002/ima.20236
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发表时间：
2010-01-01
影响因子：
3.3
通讯作者：
Muckli, Lars
中科院分区：
文献类型：
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作者：
Muckli, Lars
功能磁共振成像(FMRI)和神经电生理学(神经生理学)是测量大脑活动的两种成熟的方法。尽管这些技术的空间和时间分辨率非常不同，但两种测量都显示出高度的一致性，即绘制大脑皮层区域的特征偏好。然而，功能磁共振成像和神经生理学之间还有其他显著的区别，例如，功能磁共振成像具有很好的获得更高认知功能的能力，偏向于测量突触活动，以及对检测反馈相关活动的良好敏感性，所有这些都可以为众所周知的大脑区域如初级视觉皮质V1的功能提供新的线索。经典地认为，V1细胞的复杂感受野特性是其详尽的特征。然而，与这种观点相反，功能磁共振成像显示，V1区的反应特性在空间上是不稳定的，受上下文信息的影响，并取决于内部状态。这篇综述将重点介绍一些最引人注目的新fMRI发现，这些发现表明Vi参与了更高的认知功能。(C)2010年威利期刊公司INT J成像系统技术，20,131-139,2010；在线发表在威利国际科学(www.intercience.wiley.com)上。DOI 10.1002/ima.20236
Functional magnetic resonance imaging (fMRI) and neuron electrophysiology (neurophysiology) are two well-established ways to measure brain activity. Even though the spatial and temporal resolution of these techniques is very different, both measurements show a high level of consistency, i.e., for mapping feature preferences of cortical areas. There are, however, other striking differences between fMRI and neurophysiology, for example, fMRI has good accessibility to higher cognitive functions, a bias to measure synaptic activity, and a good sensitivity to detect feedback-related activity, all of which can shed a new light on the function of well-known brain areas like primary visual cortex, V1. Classically, it is believed that V1 cells are exhaustively characterized by their complex receptive field properties. Contrary to this view, however, fMRI shows that response properties in area V1 are spatially unstable, influenced by contextual information, and depend on internal states. This review will highlight some of the most striking new fMRI findings that show Vi is involved in higher cognitive functions. (C) 2010 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 20, 131-139, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ima.20236