Sex-ratio segregation distortion associated with reproductive isolation in Drosophila
Sex-ratio segregation distortion associated with reproductive isolation in Drosophila
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DOI：
10.1073/pnas.231478798
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发表时间：
2001-11-06
影响因子：
11.1
通讯作者：
Laurie, CC
中科院分区：
文献类型：
--
作者：
Tao, Y;Hartl, DL;Laurie, CC
性别比例扭曲是自然群体中观察到的最常见的非孟德尔隔离形式。这种情况发生的频率甚至可能比直接观察表明的更为频繁，因为性别比例偏差所造成的基因不良的群体后果预计会导致抑制因子的快速进化，从而导致被抑制或“神秘”的分离扭曲。在这里，我们报告了通过将毛里求斯果蝇基因组片段渗入模拟果蝇基因组中发现的神秘性别比例扭曲的证据。性别比例扭曲的常染色体抑制因子也与杂种男性生育能力的降低有关，它在遗传上定位于 3 号染色体中小于 80 kb 对的区域。
Sex-ratio distortion is the most common form of non-Mendelian segregation observed in natural populations. It may occur even more frequently than direct observations suggest, because the dysgenic population consequences of a biased sex ratio are expected to result in the rapid evolution of suppressors, resulting in suppressed or "cryptic" segregation distortion. Here we report evidence for cryptic sex-ratio distortion that was discovered by introgressing segments of the genome of Drosophila mauritiana into the genome of Drosophila simulans. The autosomal suppressor of sex-ratio distortion, which is also associated with a reduction in hybrid male fertility, has been genetically localized to a region smaller than 80-kb pairs in chromosome 3.