Novel Association of Smaller Anterior Chamber Width with Angle Closure in Singaporeans
Novel Association of Smaller Anterior Chamber Width with Angle Closure in Singaporeans
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DOI：
10.1016/j.ophtha.2010.02.007
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发表时间：
2010-10-01
期刊：
影响因子：
13.7
通讯作者：
Aung, Tin
中科院分区：
文献类型：
--
作者：
Nongpiur, Monisha E.;Sakata, Lisandro M.;Aung, Tin
目的：描述前房宽度（ACW）的变化，并研究其与窄角的存在的关系。设计：横断面研究。参会人员：我们从社区综合医院招募了2047名年龄在50岁或以上的受试者，并从新加坡的眼科医院招募了111名原发性闭角型（PAC）或原发性闭角型青光眼（PACG）受试者。（IOLMaster; Carl Zeiss，Jena，德国）和前段光学相干断层扫描（AS-OCT，Visante，Carl Zeiss Meditec，都柏林，CA）。使用定制软件测量ACW，ACW定义为AS-OCT扫描的水平（鼻-颞）轴上巩膜毛刺之间的距离。一只眼睛被认为有狭窄的角度，如果后小梁网是不可见的至少180度的非压痕前房角镜检查与眼睛在primary position.Main结果Measures：前房宽度和狭窄angle.Results：数据1465社区为基础的主题进行分析。女性前房宽度明显小于男性（分别为11.70 mm和11.81 mm，P
Purpose: To describe variations in anterior chamber width (ACW) and investigate its association with the presence of narrow angles.Design: Cross-sectional study. Participants: We recruited 2047 subjects aged 50 years or more from a community polyclinic and 111 subjects with primary angle closure (PAC) or primary angle closure glaucoma (PACG) from an eye hospital in Singapore.Methods: All participants underwent gonioscopy, anterior chamber depth (ACD) and axial length (AL) measurement (IOLMaster; Carl Zeiss, Jena, Germany), and anterior-segment optical coherence tomography (AS-OCT, Visante, Carl Zeiss Meditec, Dublin, CA). Customized software was used to measure the ACW, defined as the distance between the scleral spurs in the horizontal (nasal-temporal) axis of AS-OCT scans. An eye was deemed to have narrow angles if the posterior trabecular meshwork was not visible for at least 180 degrees on non-indentation gonioscopy with the eye in the primary position.Main Outcome Measures: Anterior chamber width and narrow angles.Results: Data on 1465 community-based subjects were available for analysis. Anterior chamber width was significantly smaller in women compared with men (11.70 mm vs. 11.81 mm, respectively, P