Epidemiological and morbidity assessment of Schistosoma japonicum infection in a migrant fisherman community, the Dongting Lake region, China
Epidemiological and morbidity assessment of Schistosoma japonicum infection in a migrant fisherman community, the Dongting Lake region, China
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DOI：
10.1016/s0035-9203(03)90112-x
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发表时间：
2003-03-01
影响因子：
2.2
通讯作者：
McManus, DP
中科院分区：
文献类型：
--
作者：
Li, YS;He, YK;McManus, DP
我们评估了流行病学和日本血吸虫感染相关的发病率，寄生虫学（加藤-卡茨法和毛蚴孵化试验）和超声检查在一个流动渔民社区（n = 106）从洞庭湖地区在中国2001年。该组的患病率为69.8%，平均感染强度为每克66.5个卵（epg）。男性的感染水平（77%）和强度（92.2 epg）高于女性（分别为58%和28.6 epg）。在所有年龄组中，11-20岁的受试者感染率最高（91%），感染强度最重（85.3 epg）。26%的受试者以前没有接受过血吸虫病治疗。超声检测到的实质纤维化（大于或等于II期）和脾肿大（或脾切除术）分别发生在37%和9%的受试者中。在18%的受试者中检测到门静脉扩张，58%（11/19）的门静脉扩张患者显示有实质纤维化（大于或等于II期）。这些结果表明S.尽管中国自1992年以来实施了一项由世界银行贷款资助的为期8年的日本血吸虫病控制项目，但移动的渔民的日本血吸虫感染和相关发病率仍然高得令人无法接受。显然，应该探索控制血吸虫病的新方法，特别是在像这些移动的渔民这样的社区。
We assessed the epidemiology and morbidity related to Schistosoma japonicum infection by both parasitological (Kato-Katz method and miracidium hatching test) and ultrasound examination in a migrant fisherman community (n = 106) from the Dongting Lake region in China in 2001. A prevalence of 69.8% and a mean infection intensity of 66.5 eggs per gram (epg) were recorded for this group. Males had a higher level of infection (77%) and intensity (92.2 epg) compared with females (58% and 28.6 epg, respectively). Subjects aged 11-20 years had the highest prevalence of infection (91%) and the heaviest infection intensity (85.3 epg) among all age groups. Twenty-six percent of the subjects had not been treated previously for schistosomiasis. Parenchymal fibrosis (greater than or equal to stage II) detected by ultrasound and spleen enlargement (or splenectomy) occurred in 37% and 9% of subjects, respectively. Portal vein dilation was detected in 18% subjects, and 58% (11/19) of those patients with portal vein enlargement were shown to have parenchymal fibrosis (greater than or equal to stage II). These results indicate that S. japonicum infection and related morbidity in mobile fishermen is still unacceptably high despite the fact that China has implemented a Schistosomiasis Control Project financed by a World Bank Loan for a period of 8 years since 1992. Clearly, new approaches for schistosomiasis control, especially in communities like these mobile fishermen, should be explored.