Towards the Development of A Steerable and MRI-Compatible Cardiac Catheter for Atrial Fibrillation Treatment.
Towards the Development of A Steerable and MRI-Compatible Cardiac Catheter for Atrial Fibrillation Treatment.
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开发用于心房颤动治疗的可操纵且与 MRI 兼容的心导管。
DOI：
10.1109/lra.2018.2861011
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发表时间：
2018
影响因子：
5.2
通讯作者：
Desai,JaydevP
中科院分区：
文献类型：
--
作者：
Sheng,Jun;Wang,Xuefeng;Dickfeld,Timm-MichaelL;Desai,JaydevP
为了治疗心房颤动（AFib），通常使用心导管进行射频消融，以阻断来自肺静脉的异常电信号。然而，操纵被动导管具有挑战性。此外，荧光镜引导下患者的辐射暴露一直是一个问题。为了解决这两大问题，这项工作提出了使用形状记忆合金（SMA）作为 AFib 的替代介入工具来开发可操纵且与磁共振成像（MRI）兼容的心导管。开发的心导管由被动柔性管和可操纵尖端组成。尖端由多个弯曲模块组成，每个模块由一对反向 SMA 线驱动。为了提高 SMA 驱动器的 MRI 兼容性，通过开发传导加热驱动技术显着减少 SMA 驱动所需的电流。在这封信中，介绍了心导管的设计和制造，然后对 SMA 弯曲模块进行了建模。对SMA弯曲模块的工作性能进行了实验研究。最后，在移植的心脏中进行心导管的概念验证演示。
To treat atrial fibrillation (AFib), radiofrequency ablation is usually implemented with a cardiac catheter to block abnormal electrical signals from pulmonary veins. However, it is challenging to manipulate a passive catheter. In addition, the radiation exposure to patients under fluoroscopic guidance has been a concern. To address these two major issues, this work presents the development of a steerable and magnetic resonance imaging (MRI) compatible cardiac catheter by using shape memory alloy (SMA) as an alternative interventional tool for AFib. The developed cardiac catheter is comprised of a passive and flexible tubing, and a steerable tip. The tip is composed of multiple bending modules and each module is actuated by a pair of antagonistic SMA wires. To improve the MRI-compatibility of SMA actuators, the electric current required for SMA actuation is significantly reduced by developing a technique of conductive heating actuation. In this letter, the design and fabrication of the cardiac catheter are presented, followed by modeling the SMA bending module. The working performance of the SMA bending module is experimentally studied. In the end, a proof-of-concept demonstration of the cardiac catheter is performed in an explanted heart.