Predictors of HIV and syphilis among men who have sex with men in a Chinese metropolitan city: comparison of risks among students and non-students.
Predictors of HIV and syphilis among men who have sex with men in a Chinese metropolitan city: comparison of risks among students and non-students.
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DOI：
10.1371/journal.pone.0037211
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发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Qian HZ
中科院分区：
文献类型：
--
作者：
Zhang L;Ding X;Lu R;Feng L;Li X;Xiao Y;Ruan Y;Vermund SH;Shao Y;Qian HZ
鉴于中国城市艾滋病感染率不断上升，男男性行为者(MSM)感染艾滋病毒的风险很大。青少年和成人学生经常将艾滋病毒相关风险作为性探索的一部分。我们比较了城市男男性接触者中学生和非学生感染HIV和梅毒的风险以及危险性行为。采用问卷调查的方法，于2009年在重庆市西南部的中国大都市招募自认为男男性接触者。每个参与者都完成了计算机辅助的自我访谈，收集了人口统计学和行为数据，并提供了艾滋病毒和梅毒检测的血液样本。多变量Logistic回归分析确定了HIV和梅毒感染的预测因素，同时比较了学生和非学生MSM。503名男男性接触者中，在校生占36.4%，其中在校大学生占84.2%。学生HIV感染标化患病率为5.5%(95%可信区间：2.1%-10.2%)，非学生为20.9%(95%CI：13.7%-27.5%)；梅毒标化患病率为4.4%(95%CI：0.7%-9.0%)，非学生为7.9%(95%CI：3.6%-12.9%)(P = 0.12)。两组人有相似的危险性行为，比如性伴侣的数量和用性行为换取金钱。多因素分析显示，在调整了年龄、种族和其他变量后，学生的HIV感染率低于非学生(调整后的优势比[AOR]：0.3；95%CI：0.1~0.8)。学生MSM的HIV感染率低于非学生MSM，梅毒感染率与非学生MSM相似。然而，由于学生MSM的性行为持续时间较短，高危性行为的发生率较高，学生感染艾滋病毒的风险可能比非学生高。
Men who have sex with men (MSM) are at a substantial risk of HIV, given rising HIV prevalence in urban China. Adolescent and adult students often take HIV-related risk as part of sexual exploration. We compared the risks of HIV and syphilis infections and risky sexual behaviors between student and non-student among urban MSM. Respondent driven sampling approach was used to recruit men who were self-identified as MSM in Chongqing Metropolitan City in southwestern China in 2009. Each participant completed a computer-assisted self-interview which collected demographic and behavioral data, and provided blood specimens for HIV and syphilis testing. Multivariable logistic regression analyses identified predictors for HIV and syphilis infections while comparing student and non-student MSM. Among 503 MSM participants, 36.4% were students, of whom 84.2% were in college. The adjusted prevalence of HIV infection was 5.5% (95% confidence interval [CI]: 2.1%–10.2%) in students and 20.9% (95% CI: 13.7%–27.5%) in non-students; the adjusted prevalence of syphilis was 4.4% (95% CI: 0.7%–9.0%) in students and 7.9% (95% CI: 3.6%–12.9%) in non-students (P = 0.12). Two groups had similar risky sexual behaviors such as number of sexual partners and exchanging sex for money. Multivariate analysis showed that students had lower HIV prevalence than non-students (adjusted odds ratio [AOR]: 0.3; 95% CI: 0.1–0.8) adjusting for age, ethnicity and other variables. Student MSM have lower HIV and similar syphilis prevalence compared with non-student MSM. However, due to a shorter duration of sexual experience and high prevalence of at-risk sexual behaviors among student MSM, HIV risk might be quite high in students as in non-students.
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DOI：
10.1097/qai.0b013e3181c7d72f
发表时间：
2010-02
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Li Y;Detels R;Lin P;Fu X;Deng Z;Liu Y;Tan Y;Li J;Wu Z
通讯作者：
Wu Z
影响因子：
4.9
作者：
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Sun, Gao
影响因子：
4.5
作者：
Cong L;Ono-Kihara M;Xu G;Ma Q;Pan X;Zhang D;Homma T;Kihara M
通讯作者：
Kihara M
影响因子：
1.8
作者：
Leiber, Eli;Chin, Dorothy;Guan, Jihui
通讯作者：
Guan, Jihui
影响因子：
7.7
作者：
Jiang Y;Qiu M;Zhang G;Xing W;Xiao Y;Pan P;Yao J;Ou CY;Su X
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