Feasibility of a randomized controlled trial to evaluate Text Reminders for Immunization Compliance in Kids (TRICKs)
Feasibility of a randomized controlled trial to evaluate Text Reminders for Immunization Compliance in Kids (TRICKs)
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DOI：
10.1016/j.vaccine.2012.06.058
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发表时间：
2012-08-03
期刊：
影响因子：
5.5
通讯作者：
Wittler, Robert R.
中科院分区：
文献类型：
--
作者：
Ahlers-Schmidt, Carolyn R.;Chesser, Amy K.;Wittler, Robert R.
目的：试行儿童免疫遵从性短信提醒(TICKS)项目，以评估其可行性和增加免疫覆盖率的潜力。设计：随机对照试验(RCT)。设置：儿科临床。参与者：当地医院出院的新生儿的父母，他们打算在大学资助的儿科住院医生和教职员工诊所寻求儿童保健。干预：在免疫截止日期之前发送短信提醒免疫接种。主要观察指标：2、4和6个月时收到免疫接种的及时性。结果：参与者(N=90)讲英语(83%)或西班牙语(17%)。大多数是女性(83%)，参加公共保险(59%)，并有足够的健康知识(96%)。父母已婚或未婚(62%)。超过66%的人只有高中或更少的文凭。更多的干预儿童接受了免疫接种，并使用每种方案分析“按时”：尽管没有统计学意义。限制包括样本大小，有问题的短信软件，以及40%的干预父母在7个月时失去电话服务。然而，干预后的访谈(N=18)显示出对技巧的强烈支持；83%的人认为短信提醒非常有帮助，17%的人有一定的帮助。讨论：试点测试使我们能够评估流程，包括招聘、保留和软件，这将增加随机对照试验的成功率。当移动服务中断时，需要具有内置备份系统的软件进行后续处理。然而，尽管存在局限性，短信提醒组的免疫接种率更高，尽管在统计学上没有显著意义。家长的支持和兴趣很高。需要一个动力十足的RCT，并对整个4-3-1-3-3-1系列进行随访。根据我们的结果，对于80%的功率，我们预计干预组90%的遵从性和对照组的80%的遵从性，我们需要每组219个，加上增加以解决退出和失去随访的问题。(C)2012爱思唯尔有限公司。保留所有权利。
Objective: To pilot test the Text Reminders for Immunization Compliance in Kids (TRICKs) program to evaluate its feasibility and potential to increase immunization coverage.Design: Randomized controlled trial (RCT).Setting: Pediatric clinic.Participants: Parents of newborns being discharged from a local hospital who intended to seek child health care at the University-sponsored pediatric resident and faculty clinic.Intervention: Text message immunization reminders prior to immunization due dates.Main Outcome Measures: Receipt and timeliness of immunizations at 2,4 and 6 months of age.Results: Participants (N = 90) were English (83%) or Spanish (17%) speaking. The majority were female (83%), on public insurance (59%), and had adequate health literacy (96%). Parents were married or a member of an unmarried couple (62%). Over 66% had a high school diploma or less. Greater numbers of intervention children received immunizations and were "on time" using per protocol analysis: though not statistically significance. Limitations include sample size, problematic text messaging software, and loss of phone service at 7 months for 40% of intervention parents. However, post-intervention interviews (N = 18) indicated strong support for TRICKs; 83% found the text message reminders very helpful and 17% somewhat helpful.Discussion: Pilot testing allowed us to assess processes, including recruitment, retention, and software, which will increase the success of an RCT. Software with built-in backup systems is needed for follow-up when mobile service is interrupted. However, in spite of limitations, immunization rates were higher in the text message reminder group, though not statistically significant. Parent support and interest was high. A fully powered RCT is needed with follow-up over the full 4-3-1-3-3-1 series. Based on our results, for 80% power where we expected 90% compliance in the intervention group and 80% in the control group we need 219 per group, plus increases to address drop out and loss of follow-up. (c) 2012 Elsevier Ltd. All rights reserved.