[Perfusion characteristics of renal mass with 64-slice spiral computed tomography].
[Perfusion characteristics of renal mass with 64-slice spiral computed tomography].
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发表时间：
2008-12
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通讯作者：
Hao Sun;H. Xue;Wei Liu;Yun Wang;Wen-min Zhao;Zheng-yu Jin
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作者：
Hao Sun;H. Xue;Wei Liu;Yun Wang;Wen-min Zhao;Zheng-yu Jin
目的探讨64层螺旋CT肾实质肿块的血流灌注特征。方法收集91例肾占位性病变患者。采用64层螺旋CT进行肾脏灌注扫描，以5 ml/s的速度团注造影剂50 ml（370 mgI/ml）。采用Siemens Body PCT（VB 20 B）软件计算患肾和正常肾实质和肾皮质的血流（BF）、血容量（BV）和通透性（PM），比较患肾和正常肾实质和肾皮质的血流灌注特征。结果肾透明细胞癌（RC-CC）40例，肾盂移行细胞癌（RPTCC）21例，肾血管平滑肌脂肪瘤（RAML）16例，单纯性肾囊肿（RSC）14例。1例（1.1%）患者发生技术故障。测量肿瘤实质灌注参数：RCCC、BF（93.7 +/- 20.2）ml x（100 ml）（-1）x min（-1），BV（182.0 +/- 46.6）1000：1，下午（115.7 +/-30.2）0.5 ml x（100 ml）（01）x min（-1）; RPTCC，BF（48.0 +/- 21.2）ml x（100 ml）（-1）x min（-1），BV（82.4 +/- 29.7）1000：1，下午（65.7 +/- 17.2）0.5 ml（100 ml）（-1）x min（-1）; RAML，BF（52.6 +/- 18.5）ml x（100 ml）（-1）x min（-1），BV（110.1 +/- 45.9）1000：1，下午（60.1 +/- 23.0）0.5 ml x（100 ml）（-1）x min-1; RSC，BF（7.0 +/- 6.5）ml x（100 ml）（-1）min（-1），BV（16.2 +/- 9.7）1000：1，PM（12.0 +/- 7.2）0.5 ml x（100 ml）（-1）x min（-1）。各病理组灌注参数差异有统计学意义（P0. 05）。5)正常肾与病变肾皮质之间的灌注特征。两种肾肿块实质D的血流灌注特征差异有统计学意义（P0. 05）。5）。结论：不同病理类型的肾脏肿块具有不同的灌注特征。多层螺旋CT灌注成像在肾脏肿块的鉴别诊断中具有潜在的价值。
OBJECTIVE To investigate the perfusion characteristics of renal mass parenchyma on 64-slice spiral computed tomography (CT). METHODS Totally 91 patients with renal mass were enrolled. Sixty-four slice spiral CT was used for renal perfusion scan that began with a contrast bolus injection of 50 ml (370 mgI/ml) at a rate of 5 ml/s. Perfusion characteristics, including blood flow (BF), blood volume (BV), and permeability (PM) of renal mass parenchyma and renal cortex in affected and normal kidneys were calculated from Siemens Body PCT (VB20B) software, and the perfusion characteristics among renal mass parenchyma and renal cortex in affected and normal kidneys were compared. RESULTS Renal clear cell carcinoma (RC-CC), renal pelvic transitional cell carcinoma (RPTCC), and renal angiomyolipoma (RAML) was pathologically confirmed in 40, 21, and 16 patients, respectively, while the remaining 14 patients were diagnosed as with renal simple cyst (RSC). Technical failure was experienced in 1 (1.1% ) patient. Perfusion parameters of tumor parenchyma were measured as follow: RCCC, BF (93.7 +/- 20.2) ml x (100 ml)(-1) x min(-1), BV (182.0 +/- 46.6) 1000:1, PM (115.7 +/-30.2) 0.5 ml x (100 ml)(01) x min(-1); RPTCC, BF (48.0 +/- 21.2) ml x (100 ml)(-1) x min(-1), BV (82.4 +/- 29.7) 1000:1, PM (65.7 +/- 17.2) 0.5 ml (100 ml)(-1) x min(-1); RAML, BF (52.6 +/- 18.5) ml x (100 ml)(-1) x min(-1), BV (110.1 +/- 45.9) 1000:1, PM (60.1 +/- 23.0) 0.5 ml x (100 ml)(-1) x min-1; RSC, BF (7.0 +/- 6.5) ml x (100 ml)(-1) min(-1), BV (16.2 +/- 9.7) 1000:1, PM (12.0 +/- 7.2) 0.5 ml x (100 ml) (-1) x min(-1). In all pathological groups, perfusion pa- rameters showed significant differences (P 0. 5) in perfusion characteristics between renal cortex in affected and normal kidneys. Aslo, the perfusion characteristics were significantly different between parenchyma D in any two kinds of renal masses (P 0. 5). C ONCLUSIONS: fDif-rent pathological types of renal mass have different perfusion characteristics. Perfusion imaging with multislice CT is potentially useful in the differential diagnosis of renal mass.