Computer model of ventricular interaction during left ventricular circulatory support.

Computer model of ventricular interaction during left ventricular circulatory support.
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左心室循环支持期间心室相互作用的计算机模型。

DOI:
10.1097/00002480-198907000-00086
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发表时间:
1989
期刊:
ASAIO transactions
影响因子:
--
通讯作者:
Hill,JD
Hill,JD
中科院分区:
--
文献类型:
--
作者:
Woodard,JC;Farrar,DJ;Chow,E;Santamore,WP;Burkhoff,D;Hill,JD

文献摘要

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The authors used a computer model of the heart and circulation to test the hypothesis that anatomic ventricular interactions are responsible for the observed instances of right ventricular failure during use of a left ventricular assist device. The model predicts that left ventricular pressure-unloading with a LVAD, in the presence of isolated systolic interaction, results in impairment of RV function, whereas with isolated diastolic interaction, RV function is improved. Due to competition between these two interactions, there is a negligible overall effect of ventricular anatomic interactions in determining right ventricular function in the normal heart.