Detection of porcine reproductive and respiratory syndrome virus and Mycoplasma hyorhinis antigens in pulmonary lesions of pigs suffering from respiratory distress
Detection of porcine reproductive and respiratory syndrome virus and Mycoplasma hyorhinis antigens in pulmonary lesions of pigs suffering from respiratory distress
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DOI：
10.1016/s0021-9975(96)80053-3
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发表时间：
1996-04-01
影响因子：
0.8
通讯作者：
Narita, M
中科院分区：
文献类型：
--
作者：
Kawashima, K;Yamada, S;Narita, M
对11例以严重呼吸困难或腹式呼吸为特征的现场病例进行了尸检。感染猪对猪繁殖与呼吸综合征病毒(PRRSV)有抗体。肺部病变以重度增殖性和间质性肺炎为主，轻度化脓性支气管炎。病变与PRRSV和猪鼻支原体抗原的检出部位密切相关。接种PRRSV的五头猪中有四头出现了轻微的肺炎。第五只动物死于严重的肺炎，产生了大量的猪鼻分枝杆菌培养。这些发现表明猪鼻分枝杆菌和PRRSV双重感染会导致严重的肺部病变。(C)1996年W.B.桑德斯有限公司
Eleven field cases of a disease characterized by severe dyspnoea or abdominal breathing were examined Post mortem. The affected pigs had antibody against porcine reproductive and respiratory syndrome virus (PRRSV). The predominant lung lesions were severe proliferative and interstitial pneumonia, and slight suppurative bronchopneumonia. The lesions were closely associated with the sites at which PRRSV and Mycoplasma hyorhinis antigens were detected. Four of five pigs inoculated with PRRSV developed slight pneumonitis. The fifth animal, which died of severe pneumonitis, yielded a heavy culture of M. hyorhinis. These findings demonstrate that dual infection with M. hyorhinis and PRRSV caused severe pulmonary lesions. (C) 1996 W.B. Saunders Company Limited