HIGH MALFORMATION RATES AND DECREASED MORTALITY IN INFANTS OF DIABETIC MOTHERS MANAGED AFTER THE 1ST TRIMESTER OF PREGNANCY (1956-1978)
HIGH MALFORMATION RATES AND DECREASED MORTALITY IN INFANTS OF DIABETIC MOTHERS MANAGED AFTER THE 1ST TRIMESTER OF PREGNANCY (1956-1978)
复制标题
DOI：
10.1016/0002-9378(84)90637-9
复制
发表时间：
1984-01-01
影响因子：
9.8
通讯作者：
KNOWLES, HC
中科院分区：
文献类型：
--
作者：
BALLARD, JL;HOLROYDE, J;KNOWLES, HC
在 23 年的时间里，我们收集了 182 名患有青少年糖尿病的孕妇受试者在怀孕、分娩和分娩期间的数据。糖尿病受试者通常在妊娠第一个三个月后接受评估。检查的数据包括糖尿病类别、孕产妇并发症以及婴儿发病率和死亡率。数据分2个时期进行分析：1970年前后。第2个时期，产妇羊水过多和酸中毒发生率改善，新生儿体内平衡问题没有显着改变，胎儿和新生儿综合损失率从34.7%下降到16.4%。新生儿畸形率从1.4%增加到16.8%，并且不受母亲年龄或糖尿病级别的影响。
Over a period of 23 yr, data were accumulated on 182 pregnant juvenile diabetic [human] subjects during pregnancy, labor and delivery. Diabetic subjects were evaluated generally after the 1st trimester of pregnancy. Data examined included diabetic class, maternal complications of pregnancy, and infant morbidity and mortality. Data were analyzed in 2 periods: before and after 1970. In the 2nd period, maternal polyhydramnios and acidosis rates improved, neonatal problems of homeostasis did not change significantly, and combined fetal and neonatal losses fell from 34.7-16.4%. The neonatal malformation rate increased from 1.4-16.8% and was not influenced by maternal age or diabetic class.