Evaluating long-term effects of heroin-assisted treatment:: The results of a 6-year follow-up
Evaluating long-term effects of heroin-assisted treatment:: The results of a 6-year follow-up
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DOI：
10.1159/000068811
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发表时间：
2003-04-01
影响因子：
3.9
通讯作者：
Uchtenhagen, A
中科院分区：
文献类型：
--
作者：
Güttinger, F;Gschwend, P;Uchtenhagen, A
自1994年1月以来，瑞士已对鸦片成瘾者提供海洛因辅助治疗。这是关于这种治疗形式的长期效果的第一份报告。本报告审查了1994年1月至1995年3月在瑞士参加一项涉及阿片类药物医疗处方的研究（PROVE项目）的研究对象（n = 366）。在8个治疗中心配发了鸦片剂。治疗开始后6年随访。评估了两组：自进入PROVE研究以来一直在接受海洛因辅助治疗或再次接受这种治疗的客户，以及在随访时停止海洛因辅助治疗的前客户。进行了两种比较。首先，将治疗开始时的情况与6年的随访结果进行比较，其次，将仍在接受海洛因辅助治疗的客户与已出院的客户的结果进行比较。结果发现，在随访时，仍存活的患者中有46%在接受海洛因辅助治疗。对目前生活条件的比较表明，接受治疗的人和终止治疗的人之间的差异很小。与入境时的情况相比，跟踪调查的结果显示，非法药物的使用、非法收入和与社会状况有关的大多数其他变量显著减少，但也显示失业和依赖社会福利的情况有所增加。因此，海洛因辅助治疗在长期治疗过程中是有效的，并且在治疗结束后就生活条件和非法药物的使用而言仍然有效。版权所有(C) 2003 S. Karger AG，巴塞尔
Since January 1994, heroin-assisted treatment for opiate addicts has been available in Switzerland. This is the first report of the long-term effects of this form of treatment. The report examines subjects who entered a study involving medical prescription of opiates (Projekt zur arztlichen Verschreibung von Betaubungsmittein; PROVE) in Switzerland between January 1994 and March 1995 (n = 366). Opiates were dispensed in eight treatment centres. A follow-up was conducted 6 years after treatment entry. Two groups were assessed: clients who have continuously been on heroin-assisted treatment since entry into the PROVE study or who re-entered this treatment, and ex-clients who had discontinued heroin-assisted treatment at the time of follow-up. Two kinds of comparisons were conducted. Firstly, conditions at treatment entry were compared to 6-year follow-up outcomes, and secondly, outcomes were compared between clients still on heroin-assisted treatment and those who had been discharged. It was found that 46% of the clients still alive were on heroin-assisted treatment at the time of follow-up. A comparison of the present living conditions showed very little difference between those in treatment and those who had terminated treatment. Compared to the situation at entry, the results of the follow-up showed a significant decrease in the use of illegal substances, illegal income and most other variables concerning social conditions, but they also showed an increase in unemployment and reliance on social benefits. Heroin-assisted treatment is thus efficacious in the long-term course of treatment and is still effective after termination of treatment with respect to living conditions and use of illicit substances. Copyright (C) 2003 S. Karger AG, Basel