PREVALENCE OF SCLERODERMA SPECTRUM DISORDERS IN THE GENERAL-POPULATION OF SOUTH-CAROLINA
PREVALENCE OF SCLERODERMA SPECTRUM DISORDERS IN THE GENERAL-POPULATION OF SOUTH-CAROLINA
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DOI：
10.1002/anr.1780320809
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发表时间：
1989-08-01
影响因子：
--
通讯作者：
ROSAL, EJ
中科院分区：
文献类型：
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作者：
MARICQ, HR;WEINRICH, MC;ROSAL, EJ
硬皮病谱系障碍（包括符合美国风湿病协会标准的系统性硬化症[SSc]和仅符合我们研究标准的不太典型的疾病）的患病率是在南卡罗来纳州[美国]的普通人群中随机抽样的6,998名受试者中确定的。结果表明，这些疾病的患病率可能在每10万人67至265人之间，比先前报道的明确SSc高4.9至19.2倍。SSc的不明确病例与明确病例（符合美国风湿病协会标准的病例）之比为2.5。在我们的研究之前，大多数不明确的病例未被识别，这表明需要改进硬皮病谱系障碍的早期诊断。本报告包括7例硬皮病谱系障碍患者的简史，这些病例构成了我们计算患病率的基础。
The prevalence of scleroderma spectrum disorders (including systemic sclerosis [SSc] meeting the American Rheumatism Association criteria and the less typical disorders meeting only our study criteria) was determined in a random sample of 6,998 subjects from the general population of South Carolina [USA]. The results suggest that the prevalence of these disorders may range from 67 to 265 per 100,000, which is 4.9 to 19.2 times higher than previously reported for definite SSc. The ratio of nondefinite cases to definite cases of SSc (those meeting American Rheumatism Association criteria) was 2.5. Most of the nondefinite cases were unrecognized prior to our study, which suggests the need for improved early diagnosis of scleroderma spectrum disorders. Brief histories of the 7 patients with scleroderma spectrum disorders whose cases formed the basis for our calculation of prevalence rates are included in this report.