Risk factors for suicide in bipolar disorder: a cohort study of 12 850 patients.

Risk factors for suicide in bipolar disorder: a cohort study of 12 850 patients.
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双相情感障碍自杀的危险因素:12850例患者的队列研究。

DOI:
10.1111/acps.12946
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发表时间:
2018-11
影响因子:
6.7
通讯作者:
Landén M
Landén M
中科院分区:
医学1区
文献类型:
--
作者:
Hansson C;Joas E;Pålsson E;Hawton K;Runeson B;Landén M

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双相情感障碍有很高的自杀风险。识别风险因素非常重要。本研究的目的是在一个大的双相情感障碍男性和女性队列中研究自杀的危险因素。一项使用瑞典双相情感障碍国家质量登记处(BipoläR)临床数据的前瞻性队列研究。结果变量是2004年至2014年间死亡原因登记册中记录的自杀事件。使用考克斯比例风险模型计算风险比(HR)。在12850名双相情感障碍患者(4844名男性和8006名女性)中,90名(55名男性和35名女性)在随访期间(1至10年)死于自杀。男性(HR 2.56)、独居(HR 2.45)、既往自杀企图(HR 4.10)、共病精神障碍(HR 2.64)、近期情感发作(HR 2.39)、刑事定罪(HR 4.43)、精神病住院治疗(HR 2.79)和非自愿承诺(HR 3.50)是自杀的重要危险因素。在双相情感障碍中,几个统计学上显著的自杀风险因素在男性和女性之间存在差异。双相情感障碍中自杀的风险因素包括一般与自杀相关的因素,但也包括诊断特异性因素。
Bipolar disorder carries a high risk of suicide. Identification of risk factors is important. The aim of this study was to study risk factors for suicide in a large cohort of men and women with bipolar disorder. A prospective cohort study using clinical data from the Swedish National Quality Register for Bipolar Affective Disorder (BipoläR). The outcome variable was suicide captured in the Cause of Death Register between 2004 and 2014. Hazard ratios (HR) were calculated using Cox proportional hazards models. Of 12 850 persons (4844 men and 8006 women) with bipolar disorder, 90 (55 men and 35 women) died by suicide during the follow‐up period (between 1 and 10 years). Male sex (HR 2.56), living alone (HR 2.45), previous suicide attempts (HR 4.10), comorbid psychiatric disorder (HR 2.64), recent affective episodes (HR 2.39), criminal conviction (HR 4.43), psychiatric inpatient care (HR 2.79), and involuntary commitment (HR 3.50) were significant risk factors for suicide. Several of the statistically significant risk factors for suicide in bipolar disorder differed between men and women. Risk factors for suicide in bipolar disorder include factors associated with suicide in general, but also diagnosis‐specific factors.
DOI: 10.1192/bjp.178.6.531
发表时间: 2001-06-01
影响因子: 10.5
作者:
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通讯作者: Thompson, C
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发表时间: 2001-09-01
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DOI: 10.1111/j.1399-5618.2007.00408.x
发表时间: 2007-08-01
期刊: BIPOLAR DISORDERS
影响因子: 5.4
作者:
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