Red wine procyanidins and vascular health
Red wine procyanidins and vascular health
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DOI：
10.1038/444566a
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发表时间：
2006-11-30
期刊：
影响因子：
64.8
通讯作者：
Crozier, A.
中科院分区：
文献类型：
--
作者：
Corder, R.;Mullen, W.;Crozier, A.
经常适量饮用红葡萄酒与降低冠心病风险和降低总体死亡率有关，但葡萄酒的酒精和多酚成分对这些影响的相对贡献尚不清楚。在这里，我们确定了原花青素作为红葡萄酒中的主要血管活性多酚，并表明它们在法国西南部和撒丁岛地区的葡萄酒中浓度较高，传统的生产方法确保这些化合物在葡萄酒酿造过程中有效地提取。这些区域也恰好与人口寿命的增加有关。
Regular, moderate consumption of red wine is linked to a reduced risk of coronary heart disease and to lower overall mortality, but the relative contribution of wine's alcohol and polyphenol components to these effects is unclear. Here we identify procyanidins as the principal vasoactive polyphenols in red wine and show that they are present at higher concentrations in wines from areas of southwestern France and Sardinia, where traditional production methods ensure that these compounds are efficiently extracted during vinification. These regions also happen to be associated with increased longevity in the population.