Short-term displacement and reproducibility of the breast and nodal targets under active breathing control
Short-term displacement and reproducibility of the breast and nodal targets under active breathing control
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DOI：
10.1016/j.ijrobp.2007.01.028
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发表时间：
2007-06-01
影响因子：
7
通讯作者：
Pierce, Lori J.
中科院分区：
文献类型：
--
作者：
Moran, Jean M.;Balter, James M.;Pierce, Lori J.
目的：对于接受局部乳腺放射治疗的患者，使用主动呼吸控制 (ABC) 装置，将乳房或胸壁以及内乳 (IM)、锁骨下 (ICV) 和锁骨上 (SCV) 淋巴结区域的短期位移和可重复性评估为屏气状态的函数。方法和材料：10 名患者在呼气末和 20% 屏气状态下使用 ABC 装置进行计算机断层扫描。肺活量 (VC) 的 40%、60% 和 80%。患者在治疗前以及治疗过程中的三分之一和三分之二时接受扫描。使用刚体变换以互信息作为度量对每个目标进行区域配准。结果：在呼气和 40% VC 之间，乳房或胸壁以及 IM、ICV 和 SCV 节点的前/上平均位移分别为 0.27/0.34、0.24/0.31、0.22/0.19 和 0.13/0.19 cm。在 VC 的 80% 时，乳房或胸壁、IM、ICV 和 SCV 节点的呼气平均位移分别为 0.84/.88、0.7609、0.70/0.79 和 0.54/0.56 cm 前/上。短期再现性（标准差）< 0.3 并且
Purpose: The short-term displacement and reproducibility of the breast or chest wall, and the internal mammary (IM), infraclavicular (ICV), and supraclavicular (SCV) nodal regions have been assessed as a function of breath-hold state using an active breathing control (ABC) device for patients receiving loco-regional breast radiation therapy.Methods and Materials: Ten patients underwent computed tomographic scanning using an ABC device at breath-hold states of end-exhale and 20%, 40%, 60%, and 80% of vital capacity (VC). Patients underwent scanning before treatment and at one third and two thirds of the way through treatment. A regional registration was performed for each target using a rigid-body transformation with mutual information as a metric.Results: Between exhale and 40% of VC, the mean displacement was 0.27/0.34, 0.24/0.31, 0.22/0.19, and 0.13/0.19 cm anterior/superior for the breast or chest wall, and IM, ICV, and SCV nodes, respectively. At 80% of VC, the mean displacement from exhale was 0.84/.88, 0.7609, 0.70/0.79, and 0.54/0.56 cm anterior/superior for the breast or chest wall, and IM, ICV, and SCV nodes, respectively. The short-term reproducibility (standard deviation) was < 0.3 and