RSVSim: an R/Bioconductor package for the simulation of structural variations
RSVSim: an R/Bioconductor package for the simulation of structural variations
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DOI：
10.1093/bioinformatics/btt198
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发表时间：
2013-07-01
期刊：
影响因子：
5.8
通讯作者：
Dugas, Martin
中科院分区：
文献类型：
--
作者：
Bartenhagen, Christoph;Dugas, Martin
RSVSim是一个工具，用于模拟任何基因组中各种大小的缺失、插入、倒置、串联复制和易位，这些基因组以FASTA文件或数据包的形式在R中可用。结构变异可以随机产生，基于用户提供的基因组坐标或与各种重复相关。该包还包括从真实数据集中估计结构变化大小的分布的函数。
RSVSim is a tool for the simulation of deletions, insertions, inversions, tandem duplications and translocations of various sizes in any genome available as FASTA-file or data package in R. The structural variations can be generated randomly, based on user-supplied genomic coordinates or associated to various kinds of repeats. The package further comprises functions to estimate the distribution of structural variation sizes from real datasets.