The diagnostic potential of three indirect tests for urinary schistosomiasis in Nigeria
The diagnostic potential of three indirect tests for urinary schistosomiasis in Nigeria
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DOI：
10.1016/s0001-706x(97)00102-2
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发表时间：
1997-12-01
期刊：
影响因子：
2.7
通讯作者：
Mafe, MA
中科院分区：
文献类型：
--
作者：
Mafe, MA
血吸虫病是世界热带、亚热带地区人类主要的寄生虫感染之一。这种疾病的诊断通常基于排泄物中虫卵的显微镜检测，这既费力又耗时。在尼日利亚，政府强调控制这一疾病，这就要求需要一种简单、快速、可靠和负担得起的诊断测试，以查明受感染社区和发现受感染者。采用三种尿血吸虫病的间接诊断试验：面谈技术、肉眼肉眼血尿检查和化学试剂条的使用，以血尿作为疾病指标，对尼日利亚Kainji湖地区的1056名个体进行尿血吸虫病筛查。使用过滤（虫卵计数）技术作为参考试验，测定三种试验的灵敏度。试纸条对面谈技术和目视检查的敏感性分别为69.0%、44%和38%。该试剂条测试特别适用于筛查儿童（5-19岁）。这些发现的含义进行了讨论。(C)1997年Elsevier Science B.V.
Schistosomiasis is one of the major parasitic infections of man in the tropical and subtropical areas of the world. Diagnosis of the disease is usually based on microscopic detection of eggs in excreta which is both laborious and time consuming. In Nigeria, the Government's emphasis on the control of the disease dictates the need for a simple, fast, reliable and affordable diagnostic test for the identification of infected communities and detection of infected persons. Three indirect diagnostic tests for urinary schistosomiasis: interview technique, visual examination for macrohaematuria and the use of a chemical reagent strip were employed in screening 1056 individuals of the Kainji Lake area of Nigeria for urinary schistosomiasis, using haematuria as the disease indicator. The sensitivity of the three tests were determined using the filtration (egg counting) technique as the reference test. The sensitivity of the reagent strip test was 69.0% and 44 and 38% for the interview technique and visual examination respectively. The reagent strip test was particularly useful for screening children (5-19 years old). The implication of these findings are discussed. (C) 1997 Elsevier Science B.V.