Regression-Based Pediatric Norms for the Brief Visuospatial Memory Test - Revised and the Symbol Digit Modalities Test
Regression-Based Pediatric Norms for the Brief Visuospatial Memory Test - Revised and the Symbol Digit Modalities Test
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DOI：
10.1080/13854046.2011.554445
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发表时间：
2011-01-01
影响因子：
3.9
通讯作者：
Benedict, R. H. B.
中科院分区：
文献类型：
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作者：
Smerbeck, A. M.;Parrish, J.;Benedict, R. H. B.
在成人样本中，已知简明视觉空间记忆测试-修订版（BVMTR）和符号数字模式测试（SDMT）仅经口给药对脑部疾病敏感，但尚无儿科标准。采用BVMTR和SDMT对6-17岁健康对照儿童（N = 92）的人口统计学平衡样本进行了测试。多元回归分析（MRA）被用来开发人口统计学控制的规范方程。该分析提供了方程，然后用于构建BVMTR试验1、试验2、试验3、总学习和延迟回忆指数以及SDMT总正确分数的人口统计学调整z分数。为了证明这种方法的实用性，还评估了急性播散性脑脊髓炎（ADEM）或多发性硬化症（MS）儿童的对照组。我们发现，这些视觉处理测试区分神经系统患者从控制。由于这些测试在成人多发性硬化症中得到了验证，它们可能有助于监测儿童多发性硬化症患者向成年过渡。
The Brief Visuospatial Memory Test - Revised (BVMTR) and the Symbol Digit Modalities Test (SDMT) oral-only administration are known to be sensitive to cerebral disease in adult samples, but pediatric norms are not available. A demographically balanced sample of healthy control children (N = 92) ages 6-17 was tested with the BVMTR and SDMT. Multiple regression analysis (MRA) was used to develop demographically controlled normative equations. This analysis provided equations that were then used to construct demographically adjusted z-scores for the BVMTR Trial 1, Trial 2, Trial 3, Total Learning, and Delayed Recall indices, as well as the SDMT total correct score. To demonstrate the utility of this approach, a comparison group of children with acute disseminated encephalomyelitis (ADEM) or multiple sclerosis (MS) were also assessed. We find that these visual processing tests discriminate neurological patients from controls. As the tests are validated in adult multiple sclerosis, they are likely to be useful in monitoring pediatric onset multiple sclerosis patients as they transition into adulthood.