Differences in the risk factors of reflux esophagitis according to age in Korea
Differences in the risk factors of reflux esophagitis according to age in Korea
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DOI：
10.1111/j.1442-2050.2012.01417.x
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发表时间：
2014-02-01
影响因子：
2.6
通讯作者：
Kim, H. Y.
中科院分区：
文献类型：
--
作者：
Park, C. H.;Kim, K. O.;Kim, H. Y.
在韩国，胃食管反流病的发病率一直被认为很低，但由于预期寿命延长和西化食物的摄入增加，预计韩国胃食管反流病的发病率将会增加。本研究的目的是报告韩国不同年龄的反流性食管炎（RE）危险因素的差异。我们前瞻性地招募了2008年1月至2009年2月期间在Hallym医疗中心（五个机构）的上消化道癌症监测健康促进中心就诊的RE患者。纳入的研究参与者包括742名RE患者和1484名健康对照者。青壮年组RE的独立危险因素为男性、吸烟、咖啡、体重指数25、裂孔疝、幽门螺杆菌阴性。老年组RE的危险因素为吸烟、咖啡、裂孔疝。不同年龄组发生RE的危险因素存在差异。与年轻人和成年组相比，老年组幽门螺杆菌感染并不是显著的保护因素。
The prevalence of gastroesophageal reflux disease in Korea has been believed to be low, but the incidence of gastroesophageal reflux disease in Korea is expected to increase because of the longer life expectancy and more ingestion of westernized food. The aim of this study was to report differences in the risk factors of reflux esophagitis (RE) according to age in Korea. We prospectively recruited the subjects who had RE among those who visited a health promotion center for upper gastrointestinal cancer surveillance at Hallym Medical Center (five institutions) between January 2008 and February 2009. The enrolled study participants comprised 742 subjects with RE and 1484 healthy controls. The independent risk factors of RE in young and adult group were male sex, smoking, coffee, body mass index 25, hiatal hernia, and Helicobacter pylori negativity. The risk factors of RE in elderly group were smoking, coffee, and hiatal hernia. The risk factors for RE according to age group were found to differ. In elderly group, Helicobacterpylori infection was not a significant protective factor contrary to young and adult groups.