A comparison of the simultaneous application of sclerotherapy and rubber band ligation, with sclerotherapy and rubber band ligation applied separately, for the treatment of haemorrhoids: a prospective randomized trial.
A comparison of the simultaneous application of sclerotherapy and rubber band ligation, with sclerotherapy and rubber band ligation applied separately, for the treatment of haemorrhoids: a prospective randomized trial.
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DOI：
10.1046/j.1463-1318.2003.00395.x
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发表时间：
2003-03-01
期刊：
影响因子：
--
通讯作者：
Betsis, D
中科院分区：
文献类型：
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作者：
Kanellos, I;Goulimaris, I;Betsis, D
目的：比较同时应用硬化疗法和橡皮圈结扎术与分别应用硬化疗法和橡皮圈结扎术治疗二度痔。患者和方法：在1993年至1996年期间，255名患有二度痔的患者被分为3组，每组85名患者，每个患者在一个疗程中同时接受硬化疗法治疗较小的痔疮和橡皮圈结扎治疗较大的痔疮（SCL/RBL），或者分别接受硬化疗法（SCL）或橡皮圈结扎（RBL）。结果：SCL组患者治疗后并发症发生率明显低于其他两种方法（P < 0.001），但两种方法治疗后并发症发生率差异无统计学意义。SCL/RBL治疗后症状消失率（46%）明显高于SCL治疗后（8%），P < 0.001。SCL/RBL组（46%）和RBL组（31%）之间无显著差异（P = 0.217），尽管联合治疗似乎比橡皮圈结扎更有效。SCL/RBL组中只有10%的患者在初始治疗后6-24个月需要额外治疗，而SCL组中有30%的患者需要额外治疗（P = 0.001）。SCL/RBL组与RBL组（17%）比较差异无统计学意义（P = 0.151）。结论：硬化剂加橡皮圈结扎治疗Ⅱ度痔的疗效明显优于单纯硬化剂治疗。
OBJECTIVE: To compare simultaneous application of sclerotherapy and rubber band ligation, with sclerotherapy and rubber band ligation applied separately for the treatment of 2nd degree haemorrhoids.PATIENTS AND METHODS: Between 1993 and 1996, 255 patients that suffered from 2nd degree haemorrhoids were divided into 3 groups of 85 patients, each to receive either simultaneous sclerotherapy for smaller and rubber band ligation for larger piles (SCL/RBL) in one session, or sclerotherapy (SCL), or rubber band ligation (RBL), respectively. After a period of 4 years all patients were examined and their symptoms were recorded.RESULTS: The patients of the SCL group developed significantly fewer complications after treatment compared to the other two methods (P < 0.001), which did not differ from each other. After the SCL/RBL treatment, significantly more patients were symptom free (46%) than after SCL (8%), P < 0.001. There was no significant difference between the SCL/RBL (46%) and the RBL (31%) groups (P = 0.217), although the combined treatment seemed to be more effective than rubber band ligation. Only 10% of the patients of the SCL/RBL group needed additional sessions 6-24 months after the initial treatment compared to 30% of the patients of the SCL group (P = 0.001). However, there was no significant difference between SCL/RBL and RBL (17%) groups (P = 0.151).CONCLUSION: The combination of sclerotherapy and rubber band ligation for treatment of 2nd degree haemorrhoids is significantly more efficient than sclerotherapy on its own.