Pregnancy and delivery with Kindler syndrome
Pregnancy and delivery with Kindler syndrome
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DOI：
10.1159/000099328
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发表时间：
2007-01-01
影响因子：
2.1
通讯作者：
Murata, Yuji
中科院分区：
文献类型：
--
作者：
Hayashi, Shusaku;Shimoya, Koichiro;Murata, Yuji
背景：Kindler综合征是一种罕见的常染色体隐性遗传性皮肤病，以大疱性皮肤白斑为特征。粘液性表现常见于口腔、食道、尿道和生殖器官。病例报告：一名37岁的妇女金德勒综合征在我们医院接受产前检查。她的皮肤病在怀孕和产褥期没有改变。她的妊娠过程是顺利的，但在妊娠38周时由于阴道狭窄进行了择期剖宫产。手术伤口愈合不复杂。结论：妊娠并没有加重Kindler综合征的皮肤症状。除产科指征外，对于严重生殖器病变的病例，可能有必要进行剖腹产。需要仔细的围手术期管理，以保护脆弱的皮肤和粘膜。
Background: Kindler syndrome is a rare, autosomal-recessive skin disease characterized by bullous poikiloderma. Mucosal manifestations are common that involve the oral cavity, esophagus, urethra and genital organs. Case Report: A 37-year-old woman with Kindler syndrome received prenatal care at our hospital. Her skin disease did not change during pregnancy and puerperium. Her pregnancy course was uneventful, but an elective cesarean section was performed at 38 weeks of gestation due to vaginal stenosis. Surgical wound healing was uncomplicated. Conclusion: Pregnancy did not exacerbate the cutaneous symptoms of Kindler syndrome in this case. Cesarean delivery may be necessary in cases with severe genital lesions besides obstetrical indications. Careful perioperative management is needed to protect vulnerable skin and mucosa.